该文采用偏最小二乘(partial least squares,PLS)算法分别建立山楂和焦山楂化学成分与消食健脾功效的“谱效”关系模型,辨识山楂、焦山楂消食健脾功效成分,阐明山楂炮制机制。分别制备山楂、焦山楂水提物不同极性部位及其组合,采用超高...该文采用偏最小二乘(partial least squares,PLS)算法分别建立山楂和焦山楂化学成分与消食健脾功效的“谱效”关系模型,辨识山楂、焦山楂消食健脾功效成分,阐明山楂炮制机制。分别制备山楂、焦山楂水提物不同极性部位及其组合,采用超高效液相色谱-质谱联用技术测定山楂、焦山楂水提物不同极性部位及其组合中24种化学成分的含量;复制大鼠胃肠动力障碍模型,测定胃排空率和小肠推进率比较山楂、焦山楂水提物不同极性部位及其组合对模型大鼠的影响;采用PLS算法分别建立山楂、焦山楂“谱效”关系模型。结果表明,山楂、焦山楂水提物不同极性部位及其组合中24种化学成分的含量差异明显;山楂、焦山楂水提物不同极性部位及其组合对模型大鼠的改善作用有明显差别;通过PLS模型参数辨识山楂消食健脾功效成分为牡荆素-4″-O-葡萄糖苷、牡荆素-2″-O-鼠李糖苷、新绿原酸、芦丁、没食子酸、香草酸、枸橼酸、苹果酸、奎尼酸和延胡索酸,焦山楂消食健脾功效成分为新绿原酸、隐绿原酸、芦丁、没食子酸、香草酸、枸橼酸、奎尼酸和延胡索酸。该文为阐明山楂炮制机制提供数据支撑和科学依据。展开更多
大学生“三下乡”实践具有实践育人的重要作用。“三下乡”社会实践中的中华优秀传统文化和红色文化因素是实现对大学生文化育人的重要资源和平台;也是大学生传承和创新中华传统文化和红色文化的重要载体。以某高校“三下乡”实践队实...大学生“三下乡”实践具有实践育人的重要作用。“三下乡”社会实践中的中华优秀传统文化和红色文化因素是实现对大学生文化育人的重要资源和平台;也是大学生传承和创新中华传统文化和红色文化的重要载体。以某高校“三下乡”实践队实践活动为例,实践中融入传统文化精神和红色精神,传承和创新红色基因等方面所采取的途径,在“三下乡”社会实践中实现传统文化和红色文化立德铸魂的文以化人的价值目标。The practice of “Activity of Three Kinds of Going to the Countryside” for college students plays an important role in practical education. The excellent traditional Chinese culture and red culture factors in the “Activity of Three Kinds of Going to the Countryside” social practice are important resources and platforms for achieving cultural education for college students. It is also an important carrier for college students to inherit and innovate traditional Chinese culture and red cultural colors. Taking the practical activity of the “Activity of Three Kinds of Going to the Countryside” practice team in a certain university as an example, the approach is taken to integrate traditional cultural spirit and red spirit, inherit and innovate red genes, and achieve the cultural value goal of cultivating morality and soul through traditional culture and red culture in the “Activity of Three Kinds of Going to the Countryside” social practice.展开更多
文摘该文采用偏最小二乘(partial least squares,PLS)算法分别建立山楂和焦山楂化学成分与消食健脾功效的“谱效”关系模型,辨识山楂、焦山楂消食健脾功效成分,阐明山楂炮制机制。分别制备山楂、焦山楂水提物不同极性部位及其组合,采用超高效液相色谱-质谱联用技术测定山楂、焦山楂水提物不同极性部位及其组合中24种化学成分的含量;复制大鼠胃肠动力障碍模型,测定胃排空率和小肠推进率比较山楂、焦山楂水提物不同极性部位及其组合对模型大鼠的影响;采用PLS算法分别建立山楂、焦山楂“谱效”关系模型。结果表明,山楂、焦山楂水提物不同极性部位及其组合中24种化学成分的含量差异明显;山楂、焦山楂水提物不同极性部位及其组合对模型大鼠的改善作用有明显差别;通过PLS模型参数辨识山楂消食健脾功效成分为牡荆素-4″-O-葡萄糖苷、牡荆素-2″-O-鼠李糖苷、新绿原酸、芦丁、没食子酸、香草酸、枸橼酸、苹果酸、奎尼酸和延胡索酸,焦山楂消食健脾功效成分为新绿原酸、隐绿原酸、芦丁、没食子酸、香草酸、枸橼酸、奎尼酸和延胡索酸。该文为阐明山楂炮制机制提供数据支撑和科学依据。
文摘大学生“三下乡”实践具有实践育人的重要作用。“三下乡”社会实践中的中华优秀传统文化和红色文化因素是实现对大学生文化育人的重要资源和平台;也是大学生传承和创新中华传统文化和红色文化的重要载体。以某高校“三下乡”实践队实践活动为例,实践中融入传统文化精神和红色精神,传承和创新红色基因等方面所采取的途径,在“三下乡”社会实践中实现传统文化和红色文化立德铸魂的文以化人的价值目标。The practice of “Activity of Three Kinds of Going to the Countryside” for college students plays an important role in practical education. The excellent traditional Chinese culture and red culture factors in the “Activity of Three Kinds of Going to the Countryside” social practice are important resources and platforms for achieving cultural education for college students. It is also an important carrier for college students to inherit and innovate traditional Chinese culture and red cultural colors. Taking the practical activity of the “Activity of Three Kinds of Going to the Countryside” practice team in a certain university as an example, the approach is taken to integrate traditional cultural spirit and red spirit, inherit and innovate red genes, and achieve the cultural value goal of cultivating morality and soul through traditional culture and red culture in the “Activity of Three Kinds of Going to the Countryside” social practice.
