As early as 30 years ago, it was reported that some men in the southern provinces of China became sterile, owing mainly to the consumption of raw cotton seed oil. It was later found that the cotton seed oil contains a...As early as 30 years ago, it was reported that some men in the southern provinces of China became sterile, owing mainly to the consumption of raw cotton seed oil. It was later found that the cotton seed oil contains a kind of phenolic compounds called gossypol. Experimental studies in laboratory animals and clinical trials in human males have since been conducted in many scientific institutions and hospitals. In men, it has been found that the gossypol is able to inhibit the motility of sperm, disrupt the structure of spermatozoa and arrest spermatogenesis. Clinic reports show that the gossypol could induce hypokalemia myasthenia in some of the patients, but its itiology remains unknown. Bi Xiao-feng et al. demonstrated that the Na, K-ATPase activity of kidney cortex in rat and guinea pig was inhibited展开更多
文摘As early as 30 years ago, it was reported that some men in the southern provinces of China became sterile, owing mainly to the consumption of raw cotton seed oil. It was later found that the cotton seed oil contains a kind of phenolic compounds called gossypol. Experimental studies in laboratory animals and clinical trials in human males have since been conducted in many scientific institutions and hospitals. In men, it has been found that the gossypol is able to inhibit the motility of sperm, disrupt the structure of spermatozoa and arrest spermatogenesis. Clinic reports show that the gossypol could induce hypokalemia myasthenia in some of the patients, but its itiology remains unknown. Bi Xiao-feng et al. demonstrated that the Na, K-ATPase activity of kidney cortex in rat and guinea pig was inhibited
