Danshen-Radix Salviae Miltiorrhizae，is one of the common traditional Chinese medicines，which has been used clinically in the treatment of cardiovascular diseases more than 20 centuries.The active ingredients of Dans...Danshen-Radix Salviae Miltiorrhizae，is one of the common traditional Chinese medicines，which has been used clinically in the treatment of cardiovascular diseases more than 20 centuries.The active ingredients of Danshen has been researched 5 decades by the modern methods.Many researchers investigated the pharmacological effects of water soluble ingredients of Danshen-salvianolic acids in vivo and in vitro.The results demonstrated that salvianolic acids have different pharmacological effects such as potent antioxidative effects，scavenging free radicals，protect neural cells against injuries caused by anoxia ，etc.In present paper，the pharmacological effects of salvianolic acids and the mechanisms of their actions are reviewed based on the research results obtained in our laboratory and other authors.展开更多
Ginseng has long been used as a tonic and agent for prolonging life span in chinese traditional medicine ．Using morden technology ginsenoside Rgl and Rbl were proved to be main active principles of ginseng． Both con...Ginseng has long been used as a tonic and agent for prolonging life span in chinese traditional medicine ．Using morden technology ginsenoside Rgl and Rbl were proved to be main active principles of ginseng． Both conpounds showed the same effect in improving learning and memory，increasing Bmax of M-cholinergic receptors and accelerating cerebral protein and acetylcholine biosynthesis． However， Rgl but not Rbl had immunoregulatory action in aged rats and anti-osteoporosis effect in ovariectomized rats as well as enhanced basic synaptic transmission and magnitude of LTP induced by HFS ．On the other hand， Rbl had anti-stress effects in antagonizing acute,chronic and repeated stress induced reduction of sexual behaviour and decrease of plasma andogen or estrogen．Rgl showed no such effect even aggravate stress induced damage．Rhl possessed antioxidant activity and prolong survival time of mice in cold(－℃10 )condition．There was no any anti-cold effect with Rgl .These diference of biological activities between Rgl and Rbl may be arributed to their structures containing different number of glucoses．展开更多
文摘Danshen-Radix Salviae Miltiorrhizae，is one of the common traditional Chinese medicines，which has been used clinically in the treatment of cardiovascular diseases more than 20 centuries.The active ingredients of Danshen has been researched 5 decades by the modern methods.Many researchers investigated the pharmacological effects of water soluble ingredients of Danshen-salvianolic acids in vivo and in vitro.The results demonstrated that salvianolic acids have different pharmacological effects such as potent antioxidative effects，scavenging free radicals，protect neural cells against injuries caused by anoxia ，etc.In present paper，the pharmacological effects of salvianolic acids and the mechanisms of their actions are reviewed based on the research results obtained in our laboratory and other authors.
文摘Ginseng has long been used as a tonic and agent for prolonging life span in chinese traditional medicine ．Using morden technology ginsenoside Rgl and Rbl were proved to be main active principles of ginseng． Both conpounds showed the same effect in improving learning and memory，increasing Bmax of M-cholinergic receptors and accelerating cerebral protein and acetylcholine biosynthesis． However， Rgl but not Rbl had immunoregulatory action in aged rats and anti-osteoporosis effect in ovariectomized rats as well as enhanced basic synaptic transmission and magnitude of LTP induced by HFS ．On the other hand， Rbl had anti-stress effects in antagonizing acute,chronic and repeated stress induced reduction of sexual behaviour and decrease of plasma andogen or estrogen．Rgl showed no such effect even aggravate stress induced damage．Rhl possessed antioxidant activity and prolong survival time of mice in cold(－℃10 )condition．There was no any anti-cold effect with Rgl .These diference of biological activities between Rgl and Rbl may be arributed to their structures containing different number of glucoses．
