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CRS对比CRS+IP与CRS+HIPEC治疗上皮性卵巢癌辅助化疗时间及预后的前瞻性观察研究
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作者 Somashekhar SP Ramya Y +8 位作者 Rohit Kumar C Shabber SZ Vijay A Amit R Poonam P Arun KN Ashwin KR 张凯(翻译) 李雁(审校) 《中国肿瘤临床》 CAS CSCD 北大核心 2022年第24期1268-1272,共5页
目的:完全肿瘤细胞减灭术(cytoreductive surgery,CRS)及术后辅助化疗,是晚期原发性上皮性卵巢癌(epithelial ovarian cancer,EOC)的重要预后因素。然而,EOC患者接受辅助化疗开始时机及其与预后的关系尚不明确,值得深入探讨。方法:本研... 目的:完全肿瘤细胞减灭术(cytoreductive surgery,CRS)及术后辅助化疗,是晚期原发性上皮性卵巢癌(epithelial ovarian cancer,EOC)的重要预后因素。然而,EOC患者接受辅助化疗开始时机及其与预后的关系尚不明确,值得深入探讨。方法:本研究选取2010年1月至2017年12月在印度班加罗尔马尼帕尔综合癌症中心接受完全细胞减灭术的185例晚期原发性EOC患者,其中部分患者接受腹腔化疗或辅助化疗,部分患者未接受腹腔化疗和辅助化疗。分别记录并分析术后开始进行辅助化疗的时间及其对预后的影响。结果:接受单纯CRS、CRS联合经腹腔港的腹腔内化疗(intraperitoneal chemotherapy,IP)或腹腔热灌注化疗(hyperthermic intraperitoneal chemotherapy,HIPEC)的患者分别为50例、60例和75例。CRS组术后开始接受辅助化疗的平均时间为32天,CRS+IP组为34天,CRS+HIPEC组为41天。CRS组中,术后化疗间隔时间>42天对无复发生存(relapse-free survival,RFS)期有显著影响(36个月vs. 17个月:P=0.02);在CRS+IP组中,患者RFS差异无统计学意义(35个月vs. 28个月;P=0.78);CRS+HIPEC组,RFS差异无统计学意义(35个月vs. 32个月;P=0.17)。如期行辅助化疗患者生存期较延迟化疗更好(88个月vs. 71个月,P=0.49)。结论:化疗时间延迟是单纯接受完全CRS患者RFS的不良预后因素。与非HIPEC组相比,化疗时间延迟对HIPEC组患者并未产生显著影响,其原因可能在于术中单次HIPEC弥补了化疗时间延迟带来的不利影响。 展开更多
关键词 细胞减灭术 腹腔热灌注化疗 辅助化疗 卵巢癌
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Clinical study on auricular point sticking plus Western medicine for moderate gastric cancer pain 被引量:4
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作者 Chen Li-xia Yan Feng 《Journal of Acupuncture and Tuina Science》 CSCD 2020年第4期276-280,共5页
Objective:To explore the clinical efficacy and mechanism of auricular point sticking plus Western medicine for moderate gastric cancer pain.Methods:A total of 80 patients were selected and divided into an observation ... Objective:To explore the clinical efficacy and mechanism of auricular point sticking plus Western medicine for moderate gastric cancer pain.Methods:A total of 80 patients were selected and divided into an observation group and a control group according to the random number table method,with 40 cases in each group.Patients in the control group received Western medicine treatment,while patients in the observation group received additional auricular point sticking.Both groups were treated for 2 weeks.Numeric rating scale(NRS)and Karnofsky performance status(KPS)were adopted before and after treatment.The total time and times of flare-up pain in 24 h were recorded.The cyclooxygenase-2(COX-2)and tumor necrosis factor-α(TNF-α)levels were detected.The clinical efficacy of both groups was evaluated after treatment.Results:The total effective rate of the observation group was significantly higher than that of the control group(P<0.05);after treatment,NRS scores of both groups were significantly lower than those before treatment(both P<0.05),and the score of the observation group was lower than that of the control group(P<0.05);KPS scores of both groups were significantly higher than those before treatment(both P<0.05),and the score of the observation group was higher than that of the control group(P<0.05).After treatment,the total time and flare-up times of pain during 24 h of both groups were significantly reduced(all P<0.05),and those of the observation group were significantly less than those of the control group(both P<0.05).After treatment,the COX-2 and TNF-αlevels of both groups were significantly reduced(all P<0.05),and were lower in the observation group than in the control group(all P<0.05).Conclusion:The clinical efficacy of auricular point sticking plus Western medicine for moderate gastric cancer pain is valid.This combined treatment can alleviate cancer pain and improve patients'quality of life,which may be related to its ability to reduce COX-2 and TNF-αlevels. 展开更多
关键词 Acupoint Therapy Auricular Point Sticking Otopoint Spleen(CO13) Otopoint Stomach(CO4) Otopoint Shenmen(TF4) Pain Measurement Stomach Neoplasms Cancer Pain
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Clinical study on Tuina plus physical agents for lateral collateral ligament injury of ankle in gymnasts 被引量:1
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作者 HU Lijun WANG Junliang +3 位作者 LIU Gang LIU Kunpeng GU Fei ZHANG Kaiwei 《Journal of Acupuncture and Tuina Science》 CSCD 2022年第4期309-315,共7页
Objective To compare the efficacy of Tuina(Chinese therapeutic massage)plus physical agents and physical agents alone for lateral collateral ligament injury of ankle in gymnasts,and to explore the feasibility of Tuina... Objective To compare the efficacy of Tuina(Chinese therapeutic massage)plus physical agents and physical agents alone for lateral collateral ligament injury of ankle in gymnasts,and to explore the feasibility of Tuina for injury intervention in competitive athletes.Methods A total of 64 gymnasts with types Ⅰ-Ⅱ lateral collateral ligament injury of ankle were selected and divided into a control group and an observation group according to a full analysis set based on the intention-to-treat principle,with 32 cases in each group.Patients in the control group received ultrasound and microwave treatment,while those in the observation group received additional Tuina manipulations.The efficacy was evaluated by total effective rate,visual analog scale(VAS)score,and American Orthopedic Foot and Ankle Society ankle-hindfoot scale(AOFAS-AHS)score.Results The total effective rate was 96.9% in the observation group and 90.6% in the control group.There was no statistical difference in the total effective rate between the two groups(P>0.05).The markedly effective rate was 75.0% in the observation group and 46.9% in the control group.The markedly effective rate in the observation group was higher than that in the control group(P<0.05).After treatment,the VAS scores of both groups showed a downward trend,and there were statistical differences between different treatment time points in the same group(P<0.05).After one and three months of treatment,the VAS scores of the observation group were lower than those of the control group(P<0.05).There were statistical differences in the AOFAS-AHS score before and after treatment within the same group(P<0.05).After one month of treatment,there was no statistical difference in the AOFAS-AHS score between the two groups(P>0.05).After three months of treatment,the AOFAS-AHS score in the observation group was higher than that in the control group,indicating statistical significance(P<0.05).There was an interaction between time and group(P<0.05).Conclusion Tuina plus physical agents can impro 展开更多
关键词 TUINA MASSAGE Sprains and Strains Ankle Injuries Visual Analog Scale Lateral Ligament Ankle GYMNASTICS
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Observation on efficacy of thumbtack needle combined with pediatric Tuina for constipation in children caused by liver depression and Qi stagnation 被引量:1
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作者 SHEN Qinghe GUAN Zhimin +2 位作者 LI Yan HAO Chunhua ZHANG Kaiwei 《Journal of Acupuncture and Tuina Science》 CSCD 2022年第4期316-320,共5页
Objective To observe the clinical effect of thumbtack needles combined with pediatric Tuina(Chinese therapeutic massage)for constipation in children caused by liver depression and Qi stagnation.Methods A total of 60 c... Objective To observe the clinical effect of thumbtack needles combined with pediatric Tuina(Chinese therapeutic massage)for constipation in children caused by liver depression and Qi stagnation.Methods A total of 60 children with constipation caused by liver depression and Qi stagnation were randomly divided into a combined group and a Tuina group,with 30 cases in each group.The cases in the Tuina group were treated with pediatric Tuina,while those in the combined group were treated with additional thumbtack needle therapy.We observed the clinical efficacy and the change in the number of spontaneous bowel movements per week before and after treatment.Results After treatment,the cure rate and the total effective rate in the combined group were higher than in the Tuina group,showing statistical significance(P<0.05).Compared with the same group before treatment,the number of spontaneous bowel movements per week in both groups increased after treatment(P<0.05).With the progression of treatment,the number of spontaneous bowel movements per week increased in both groups,and the number in the combined group was more than that in the Tuina group,showing statistical significance(P<0.01).Conclusion Thumbtack needles combined with pediatric Tuina is more effective than pediatric Tuina alone in the treatment of constipation in children caused by liver depression and Qi stagnation. 展开更多
关键词 TUINA MASSAGE Pediatric Massage(Tuina) Embedding Therapy Intradermal Needle Therapy Liver Depression and Qi Stagnation CONSTIPATION CHILD
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Research on clinical application of manual therapy to tumor-related adverse reactions
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作者 YAO Chongjie LU Zhizhen +5 位作者 ZHANG Shuaipan KONG Lingjun ZHU Qingguang CHENG Yanbin FANG Min ZHANG Kaiwei 《Journal of Acupuncture and Tuina Science》 CSCD 2022年第4期321-328,共8页
Objective To analyze the clinical application of manual therapy(MT)to tumor-related adverse reactions via summarizing the research at home and abroad,in order to provide more theoretical evidence for the clinical prom... Objective To analyze the clinical application of manual therapy(MT)to tumor-related adverse reactions via summarizing the research at home and abroad,in order to provide more theoretical evidence for the clinical promotion of MT.Methods We searched 7 Chinese and English databases,including China National Knowledge Infrastructure(CNKI),Wanfang Academic Journal Full-text Database(Wanfang),Chongqing VIP Database(CQVIP),PubMed,Excerpta Medica Database(EMBASE),Ovid and EBSCO.The publication date was between the establishment date of the database and December 31,2020.We screened the literature according to the inclusion and exclusion criteria,and then sorted and analyzed the selected information.Results A total of 46 papers were analyzed.Most studies focused on the adverse reactions in breast cancer patients.MT interventions demonstrated the best efficacy for fatigue,followed by pain,depression and anxiety.In different MT interventions,Tuina(Chinese therapeutic massage)was mainly adopted for fatigue,pain,anxiety,depression,and limb dysfunctions.Acupoint pressing was mainly adopted for gastrointestinal and psychological problems such as abdominal bloating,insomnia,depression and anxiety.The application of reflexotherapy was similar to that of Tuina.Conclusion MT can alleviate various adverse reactions by effectively relieving patients’somatic symptoms and improving their psychological states and overall functions.It can be popularized as a significant non-drug therapy.Currently,however,the clinical application of MT is neither extensive nor has sufficient basic research.Consequently,we should attach importance to this application. 展开更多
关键词 Manual Therapies TUINA MASSAGE Acupoint Pressure Therapy REFLEXOTHERAPY TUMOR Adverse Reaction LITERATURE
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吸附和生物降解同步(SAB)处理含金属氰化物废水
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作者 张凯顺(翻译 《黄金》 CAS 北大核心 2008年第10期62-62,共1页
文中介绍了活性炭吸附和荧光假单胞菌生物降解分别进行及二种方法同步(SAB)进行处理含金属氰化物过程及效果,并对其进行了对比研究。在初始CN^-质量浓度为50,100,200,300mg/L及初始pH值为6的条件下.用亚铁氰化物溶液进行了各项... 文中介绍了活性炭吸附和荧光假单胞菌生物降解分别进行及二种方法同步(SAB)进行处理含金属氰化物过程及效果,并对其进行了对比研究。在初始CN^-质量浓度为50,100,200,300mg/L及初始pH值为6的条件下.用亚铁氰化物溶液进行了各项试验。将亚铁氰化物作为唯一氮源,在振荡60h后,观察荧光假单胞菌埘业铁氰化物降解率分别为96.4%、94.1%、86.2%、69.3%。 展开更多
关键词 金属氰化物 活性炭吸附 生物降解 解同步 荧光假单胞菌 废水 铁氰化物 氰化物溶液
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微波辅助氧化从含硫氰酸盐溶液中回收氰化物
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作者 张凯顺(翻译 《黄金》 CAS 北大核心 2008年第9期51-51,共1页
贵金属提取通常是使用过量的氰化物从矿石中浸出金和银。氰化物消耗往往是总生产成本中最重要的组成部分。目前,从硫氰酸盐和热力学性质稳定的氰络合物中回收氰化物工艺在工业上已经应用。但是,有许多生产厂家,还在采用成本较高的氰... 贵金属提取通常是使用过量的氰化物从矿石中浸出金和银。氰化物消耗往往是总生产成本中最重要的组成部分。目前,从硫氰酸盐和热力学性质稳定的氰络合物中回收氰化物工艺在工业上已经应用。但是,有许多生产厂家,还在采用成本较高的氰化物降解工艺。 展开更多
关键词 硫氰酸盐 氰化物 微波辅助 盐溶液 金属提取 生产成本
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金矿石堆浸厂浸渣及污水的净化
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作者 张凯顺(翻译 《黄金》 CAS 北大核心 2008年第9期51-51,共1页
矿山废弃物(处理)技术工程(MWTP)项目之一的堆浸场氰化物生物降解净化,在位于内华达州东北部的Coaez金矿(CGM)进行。普莱泽多姆公司(Placer Dome,Inc.)与Kennecott勘探有限责任公司投资,共拥有CGM的60%股份。这个项目是MWT... 矿山废弃物(处理)技术工程(MWTP)项目之一的堆浸场氰化物生物降解净化,在位于内华达州东北部的Coaez金矿(CGM)进行。普莱泽多姆公司(Placer Dome,Inc.)与Kennecott勘探有限责任公司投资,共拥有CGM的60%股份。这个项目是MWTP11号项目的第二部分,正在内达华州斯帕克斯市的McClelland实验室,进行大型的柱浸试验研究。 展开更多
关键词 金矿石 净化 堆浸厂 污水 浸渣 矿山废弃物 生物降解
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