Objective To investigate the changes of neuronal activation in taste related nuclei following intraoral taste stimulation with binary taste mixtures of sucrose and NaCl. Methods Neuronal activation in response to...Objective To investigate the changes of neuronal activation in taste related nuclei following intraoral taste stimulation with binary taste mixtures of sucrose and NaCl. Methods Neuronal activation in response to intraoral taste stimulation with 0.5 mol·L -1 sucrose, 0.3 mol·L -1 NaCl, sucrose+NaCl mixture and distilled water was evaluated in taste related nuclei by using c Fos like immunoreactivity in the rats deprived of water overnight. Results The consumption of sucrose+NaCl mixture was lower than that of sucrose solution. Intraoral sucrose or NaCl stimulation induced more c FLI than distilled water in the external lateral subnucleus of the rostral parabrachial nucleus (PBN), but the c FLI induced by intraoral sucrose+NaCl mixture stimulation was less than that induced by sucrose solution in this subnucleus. Compared with distilled water, the intraoral sucrose or sucrose+NaCl mixture stimulation induced more c FLI in the central amygdala. ConclusionThese results suggest that salty taste has a suppressive effect on the neuronal activations induced by sweet taste in the external lateral subnucleus of rostral PBN in rats.展开更多
基金ThisworkwassupportedbytheNationalNaturalScienceFoundationofChina (No .30270454)andtheScienceandTechnologyResearchDevelopmentProjectofShaanxiProvince (No .2 0 0 2K1 0 G7 0 1 )
文摘Objective To investigate the changes of neuronal activation in taste related nuclei following intraoral taste stimulation with binary taste mixtures of sucrose and NaCl. Methods Neuronal activation in response to intraoral taste stimulation with 0.5 mol·L -1 sucrose, 0.3 mol·L -1 NaCl, sucrose+NaCl mixture and distilled water was evaluated in taste related nuclei by using c Fos like immunoreactivity in the rats deprived of water overnight. Results The consumption of sucrose+NaCl mixture was lower than that of sucrose solution. Intraoral sucrose or NaCl stimulation induced more c FLI than distilled water in the external lateral subnucleus of the rostral parabrachial nucleus (PBN), but the c FLI induced by intraoral sucrose+NaCl mixture stimulation was less than that induced by sucrose solution in this subnucleus. Compared with distilled water, the intraoral sucrose or sucrose+NaCl mixture stimulation induced more c FLI in the central amygdala. ConclusionThese results suggest that salty taste has a suppressive effect on the neuronal activations induced by sweet taste in the external lateral subnucleus of rostral PBN in rats.
