目的:观察针刺治疗睡眠觉醒时相延迟障碍(DSWPD)的临床疗效。方法:将84例DSWPD患者随机分为观察组(42例,脱落2例)和对照组(42例,脱落3例)。两组均予睡眠卫生健康宣教,在此基础上,观察组针刺申脉、照海、合谷、太冲、足三里、三阴交,对...目的:观察针刺治疗睡眠觉醒时相延迟障碍(DSWPD)的临床疗效。方法:将84例DSWPD患者随机分为观察组(42例,脱落2例)和对照组(42例,脱落3例)。两组均予睡眠卫生健康宣教,在此基础上,观察组针刺申脉、照海、合谷、太冲、足三里、三阴交,对照组于相同穴位予安慰针刺,均治疗8周,第1~4周隔日1次,每周3次;第5~8周隔2 d 1次,每周2次。治疗前后,观察两组患者睡眠体动记录仪(ACT)客观睡眠指标(总卧床时间、总睡眠时间、睡眠效率、觉醒次数、入睡后觉醒时间)及血浆皮质醇(CORT)含量;治疗前后及治疗结束后1、3个月随访时,观察两组患者早-晚问卷(MEQ)、失眠严重程度指数(ISI)、疲劳严重程度量表(FSS)、Epworth嗜睡量表(ESS)评分。结果:与治疗前比较,治疗后观察组总睡眠时间延长、睡眠效率提高、觉醒次数减少、入睡后觉醒时间缩短(P<0.01,P<0.05),且治疗后观察组上述指标均优于对照组(P<0.01,P<0.05)。与治疗前比较,两组治疗后及观察组随访1、3个月MEQ评分升高(P<0.01),且治疗后各时间点观察组MEQ评分均高于对照组(P<0.01)。观察组治疗后ISI、FSS、ESS评分及随访1、3个月ISI、ESS评分均较治疗前下降(P<0.01,P<0.05),且观察组治疗后各时间点ISI、FSS、ESS评分均低于对照组(P<0.01,P<0.05)。治疗后,观察组血浆CORT含量较治疗前降低(P<0.01),且低于对照组(P<0.05)。结论:针刺可改善DSWPD患者睡眠觉醒时相,提高其睡眠质量和日间功能状态,其机制可能与降低血浆CORT含量相关。展开更多
Objective To observe the effect of electroacupuncture(EA)at different time points during the perioperative period on the recovery of gastrointestinal function after gastrointestinal malignant neoplasms surgery.Methods...Objective To observe the effect of electroacupuncture(EA)at different time points during the perioperative period on the recovery of gastrointestinal function after gastrointestinal malignant neoplasms surgery.Methods Sixty-three patients who needed radical surgery for gastrointestinal tumors were randomized into a control group,treatment group 1(postoperative EA group),and treatment group 2(intraoperative and postoperative EA group).The control group received surgery and conventional Western medicine treatment,and treatment groups 1 and 2 received additional EA treatment at different time points.The initial flatus time after the surgery,visual analog scale(VAS)score at different time points after the surgery,the proportion of using patient-controlled analgesia(PCA)after the surgery,and the times of adding analgesics were observed in the three groups.Results The initial flatus time after the surgery was earlier in treatment groups 1 and 2 than in the control group(P<0.05);the difference between treatment groups 1 and 2 was statistically insignificant(P>0.05).The VAS score was lower in treatment group 2 than in the control group at 6,12,24,and 72 h after the surgery(P<0.05);the VAS score was lower in treatment group 1 than in the control group only at 72 h after the surgery(P<0.05).There were no significant differences in the rate of using PCA among the three groups(P>0.05).Regarding the times of adding analgesics,it was less in treatment group 2 than in the control group at 12 h after the surgery(P<0.05).Conclusion Either EA during and after the surgery or only after the surgery can hasten the initial flatus and boost the recovery of gastrointestinal function in patients after radical resection of gastrointestinal neoplasms.Successive EA during and after the surgery should be superior to postoperative EA regarding the analgesic effect after the surgery.展开更多
文摘目的:观察针刺治疗睡眠觉醒时相延迟障碍(DSWPD)的临床疗效。方法:将84例DSWPD患者随机分为观察组(42例,脱落2例)和对照组(42例,脱落3例)。两组均予睡眠卫生健康宣教,在此基础上,观察组针刺申脉、照海、合谷、太冲、足三里、三阴交,对照组于相同穴位予安慰针刺,均治疗8周,第1~4周隔日1次,每周3次;第5~8周隔2 d 1次,每周2次。治疗前后,观察两组患者睡眠体动记录仪(ACT)客观睡眠指标(总卧床时间、总睡眠时间、睡眠效率、觉醒次数、入睡后觉醒时间)及血浆皮质醇(CORT)含量;治疗前后及治疗结束后1、3个月随访时,观察两组患者早-晚问卷(MEQ)、失眠严重程度指数(ISI)、疲劳严重程度量表(FSS)、Epworth嗜睡量表(ESS)评分。结果:与治疗前比较,治疗后观察组总睡眠时间延长、睡眠效率提高、觉醒次数减少、入睡后觉醒时间缩短(P<0.01,P<0.05),且治疗后观察组上述指标均优于对照组(P<0.01,P<0.05)。与治疗前比较,两组治疗后及观察组随访1、3个月MEQ评分升高(P<0.01),且治疗后各时间点观察组MEQ评分均高于对照组(P<0.01)。观察组治疗后ISI、FSS、ESS评分及随访1、3个月ISI、ESS评分均较治疗前下降(P<0.01,P<0.05),且观察组治疗后各时间点ISI、FSS、ESS评分均低于对照组(P<0.01,P<0.05)。治疗后,观察组血浆CORT含量较治疗前降低(P<0.01),且低于对照组(P<0.05)。结论:针刺可改善DSWPD患者睡眠觉醒时相,提高其睡眠质量和日间功能状态,其机制可能与降低血浆CORT含量相关。
文摘Objective To observe the effect of electroacupuncture(EA)at different time points during the perioperative period on the recovery of gastrointestinal function after gastrointestinal malignant neoplasms surgery.Methods Sixty-three patients who needed radical surgery for gastrointestinal tumors were randomized into a control group,treatment group 1(postoperative EA group),and treatment group 2(intraoperative and postoperative EA group).The control group received surgery and conventional Western medicine treatment,and treatment groups 1 and 2 received additional EA treatment at different time points.The initial flatus time after the surgery,visual analog scale(VAS)score at different time points after the surgery,the proportion of using patient-controlled analgesia(PCA)after the surgery,and the times of adding analgesics were observed in the three groups.Results The initial flatus time after the surgery was earlier in treatment groups 1 and 2 than in the control group(P<0.05);the difference between treatment groups 1 and 2 was statistically insignificant(P>0.05).The VAS score was lower in treatment group 2 than in the control group at 6,12,24,and 72 h after the surgery(P<0.05);the VAS score was lower in treatment group 1 than in the control group only at 72 h after the surgery(P<0.05).There were no significant differences in the rate of using PCA among the three groups(P>0.05).Regarding the times of adding analgesics,it was less in treatment group 2 than in the control group at 12 h after the surgery(P<0.05).Conclusion Either EA during and after the surgery or only after the surgery can hasten the initial flatus and boost the recovery of gastrointestinal function in patients after radical resection of gastrointestinal neoplasms.Successive EA during and after the surgery should be superior to postoperative EA regarding the analgesic effect after the surgery.
