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女性生殖道解脲支原体感染对妊娠结局的影响 被引量:13
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作者 杨祖菁 蔡月娥 +1 位作者 王磊 姜国 《中国医师杂志》 CAS 2003年第4期475-477,共3页
目的 调查妊娠期生殖道解脲支原体感染对孕产妇和新生儿的影响。方法 应用聚合酶链反应技术对妊娠期阴道分泌物测定 ,分成感染组和对照组进行结果分析。结果  2 430份阴道分泌物作解脲支原体的检测 ,检出阳性为 62 4例 ,妊娠中期感染... 目的 调查妊娠期生殖道解脲支原体感染对孕产妇和新生儿的影响。方法 应用聚合酶链反应技术对妊娠期阴道分泌物测定 ,分成感染组和对照组进行结果分析。结果  2 430份阴道分泌物作解脲支原体的检测 ,检出阳性为 62 4例 ,妊娠中期感染率 2 4 5 3% ,晚期妊娠 2 8 86% ,总感染率为 2 5 68% ,解脲支原体有自然转阴性率为 74 5 1% (193/2 5 9) ,转阳性率为 15 2 1% (7/4 6)。解脲支原体感染中有胎膜早破 184例 (32 0 5 % ) ,明显高于对照组 2 0例 (2 2 % )P <0 0 5。对胎儿新生儿的影响主要为新生儿出生体重下降 ,感染组小于胎龄儿发生率明显高于对照组 (4 5 /5 74对 2 /10 0 ) P <0 0 5 ,围产儿死亡率感染组为 2 4 39‰并与对照组比较差别不明显 ,但明显高于同期分娩的围产儿死亡率 7 742‰ ,P值 <0 0 1。评分。结论 妊娠期感染解脲支原可引起胎膜早破增加 。 展开更多
关键词 解脲支原体感染 妊娠结局 小于胎龄
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喂养与生育力的探讨 被引量:1
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作者 金碧华 姜国 +3 位作者 潘琢如 杨淑蓉 虞菏莲 张逸 《上海第二医科大学学报》 CSCD 2000年第2期125-128,共4页
目的研究哺乳期妇女不同喂养方式的生育力恢复。方法 104 例对象分为母乳、混合、人工喂养三组,观察和记录宫颈粘液,其中33例连续测定了血生乳素和雌二醇。32例测定了尿雌激素和(或)孕二醇。结果 产后第1次来经的平均日... 目的研究哺乳期妇女不同喂养方式的生育力恢复。方法 104 例对象分为母乳、混合、人工喂养三组,观察和记录宫颈粘液,其中33例连续测定了血生乳素和雌二醇。32例测定了尿雌激素和(或)孕二醇。结果 产后第1次来经的平均日三组分别为198.16、 175.35和91.44d,第2次与第1次月经间隔的平均日三组分别为67.50、28.57和23.28d,经统计分析,母乳、混合与人工喂养组之间都有显著差异(P<0.05)。宫颈粘液法估计月经恢复的正确性为86.53%,血生乳素和雌二醇的比例预测月经恢复的灵敏度达93.24%、特异性为89.28%,12例混合喂养者尿孕二醇水平均<7.10μmol/24h,表明无排卵发生。结论 应用宫颈粘液观察法了解生育力简单、正确,妇女自己能掌握,可推广。遇到识别粘液有困难时,作内分泌测定,可了解生育力的恢复。 展开更多
关键词 哺乳期 喂养 生育力
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比林斯法在哺乳期应用的实验和临床研究
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作者 金碧华 姜国 +5 位作者 吴靖川 申屠敏 朱志宾 郑玲珍 张逸 颜洁敏 《生殖与避孕》 CAS CSCD 北大核心 2002年第3期156-160,共5页
目的 :观察比林斯生育调节法 (BOM)在哺乳期避免妊娠的可行性和有效性 ,寻找监测哺乳期生育力恢复的指标。方法 :对比研究比林斯法和 IUD法在 1 2个月中的意外妊娠率、停用率和续用率。测定血生乳素、雌二醇用以估计月经恢复 ;检测尿雌... 目的 :观察比林斯生育调节法 (BOM)在哺乳期避免妊娠的可行性和有效性 ,寻找监测哺乳期生育力恢复的指标。方法 :对比研究比林斯法和 IUD法在 1 2个月中的意外妊娠率、停用率和续用率。测定血生乳素、雌二醇用以估计月经恢复 ;检测尿雌激素和孕二醇 ,确定第 2次月经前是否排卵。结果 :哺乳期比林斯法和 IUD法两组妇女分别观察了 2 1 9例和 2 0 0例。妊娠率、停用率和续用率分别为 1 .43 %、1 .5 4 %,8.5 3 %、8.87%和 90 .1 7%、91 .3 5 %,两组间无统计学差异 (P>0 .0 5 )。同期进行的 90例和 2 75次血生乳素、雌二醇的测定发现 ,二者比例以 0 .3 5作为月经恢复的指标。6 1例尿雌激素和孕二醇测定表明 ,宫颈粘液类型与激素水平吻合外 ;混合喂养妇女第 2次月经前排卵发生率为 47.0 5 %。结论 :(1 ) BOM用于哺乳期避孕的效率如同 IUD法 ,也能被哺乳期妇女接受。 (2 )血生乳素和雌二醇测定可估计哺乳期妇女月经恢复 ,方法简单 ,可应用于临床。 (3 )混合喂养有延迟哺乳期生育的作用。 展开更多
关键词 哺乳期 比林斯法 临床 实验
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The Application of Billings for Fertility RegulationMethod during the Period of Breastfeeding
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作者 金碧华 姜国 +3 位作者 潘琢如 颜洁敏 彭守静 陆仁康 《Journal of Reproduction and Contraception》 CAS 1999年第3期163-169,共7页
In order to adopt Billings Method for fertility regulation during the period of breast feeding, cervical mucus was observed and monitored in 61 breast feeding mothers.Urine estrogen and /or pregnanediol ... In order to adopt Billings Method for fertility regulation during the period of breast feeding, cervical mucus was observed and monitored in 61 breast feeding mothers.Urine estrogen and /or pregnanediol were/was measured in 15 breast feeding mothers. Observations on cervical mucus during 244 months were collected. The type of dry or no mucus was observed in 75.27% fully breast feeding mothers. Constant unchanging mucus was observed in 69.39% partially breast feeding mothers. Developmental changing mucus was observed in 79.25% of mothers bottle feeding their infants. According to the record on cervical mucus within 6 months postpartum, 97.14% of the cervical mucus was consistent with normal menstrual cycles. Urine estrogen and /or pregnanediol were/was measured in 15 breast feeding mothers. The level of estrogen in urine averaged 0.08 μmol/24 h in fully breast feeding mothers and 0.14 μmol/24 h in partially breast feeding mothers.The peak level averaged 0.21 μmol/24 h in bottle feeding mothers.The pregnanediol level was determined to confirm ovulation in bottle feeding mothers. The average levels of cut off and the period of ovulation in 6 bottle feeding mother were 7 μmol/24 h and 9 μmol/24 h respectively.Measurement of urine estrogen and pregnanediol level all matched with cervical mucus appearances. Conclusion: Billings Method is a simple, scientific method for contraception without side effects during breast feeding period. 展开更多
关键词 Breast feeding Billings Method CLINIC Experiment
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The Clinical and Experimental Research on Billings Ovulation Method During Breastfeeding
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作者 金碧华 姜国 +5 位作者 吴靖川 申屠敏 朱志宾 郑玲珍 张逸 颜洁敏 《Journal of Reproduction and Contraception》 CAS 2002年第2期90-97,共8页
Objective The effectiveness and acceptability of Billings Ovulation Method (BOM) during breastfeeding were studied. At the same time, the monitoring indexes of fertility return were studied.Methods It was a clinical c... Objective The effectiveness and acceptability of Billings Ovulation Method (BOM) during breastfeeding were studied. At the same time, the monitoring indexes of fertility return were studied.Methods It was a clinical comparative study of BOM and IUD containing copper (200mm 2). The annual rate of pregnancy, discontinuation rate and continuation rate in the two groups was determined. The serum prolactin and estradiol in 90 breastfeeding mothers and urine estrogen and pregnanediol in different feeding mothers were measured.Results There were 219 subjects in the BOM group and 200 in the IUD group. The pregnancy rate in this two groups was 1. 43% and 1. 54% respectively. The rates of discontinuation and continuation in the IUD group were:8. 87% and 91. 35% as well as in the BOM group were 8. 53% and 90. 17% respectively. Neither result was statistically significant (P>0. 05). The experimtal research showed that menses return was well estimated by 0. 35 ratio of serum prolactin vs. estrodiol. Sensitivity and specificity was 94. 61% and 84. 61% respectively. It also indicated that (1) the levels of urine hormone were closely related to the patterns of cervical mucus and (2) the incidence of ovulating before the second return of menses in partially breastfeeding mothers was much lower than that of bottle-feeding mothers (47. 05% vs. 94. 20%). Conclusion BOM is a simple, reliable and well accepted contraceptive method of during breastfeeding. If it can be combined with the measurement of serum prolactin/ estradiol, the date of menses return will be determined more easily. Encouraging mothers to breast-feed will be beneficial to the health of both babies and mothers and delay the fertility return of mothers. 展开更多
关键词 BREASTFEEDING Billings ovulation method (BOM) contraceptive method
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Billings生育调节法应用于哺乳期妇女的临床实验研究
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作者 金碧华 姜国 +3 位作者 潘琢如 颜洁敏 彭守静 陆仁康 《生殖与避孕》 CAS CSCD 北大核心 1999年第4期239-241,共3页
近年来,我国响应世界卫生组织和联合国儿童基金会的号召,为实现产后4~6个月内完全母乳喂养率达80%的总目标而努力。文献报道完全母乳喂养并处于闭经阶段4~6个月内,采用生育调控法,其避孕效果可达98%[1]。我院在19... 近年来,我国响应世界卫生组织和联合国儿童基金会的号召,为实现产后4~6个月内完全母乳喂养率达80%的总目标而努力。文献报道完全母乳喂养并处于闭经阶段4~6个月内,采用生育调控法,其避孕效果可达98%[1]。我院在1995年建立了爱婴医院,为了保护婴儿... 展开更多
关键词 哺乳期 BILLINGS 生育调节法 实验研究 避孕
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