Objective To explore clinical features and severity of chronic graft-versus-host disease(cGVHD)after chemotherapy plus donor lymphocyte infusion(ChemoDLI)in a consecutive cohort of acute leukemia patients with minimal...Objective To explore clinical features and severity of chronic graft-versus-host disease(cGVHD)after chemotherapy plus donor lymphocyte infusion(ChemoDLI)in a consecutive cohort of acute leukemia patients with minimal residual disease(MRD)positive after allogeneic hematopoietic stem cell transplantation(allo-HSCT).Methods The global scoring system proposed by National Institutes of Health(NIH)Consensus Conference was used to identify the characteristics and severity of cGVHD in patients with MRD positive after Chemo-DLI.Results 54(59.3%)patients were diagnosed with cGVHD after Chemo-DLI.展开更多
文摘Objective To explore clinical features and severity of chronic graft-versus-host disease(cGVHD)after chemotherapy plus donor lymphocyte infusion(ChemoDLI)in a consecutive cohort of acute leukemia patients with minimal residual disease(MRD)positive after allogeneic hematopoietic stem cell transplantation(allo-HSCT).Methods The global scoring system proposed by National Institutes of Health(NIH)Consensus Conference was used to identify the characteristics and severity of cGVHD in patients with MRD positive after Chemo-DLI.Results 54(59.3%)patients were diagnosed with cGVHD after Chemo-DLI.