目的:探讨血清骨唾液酸蛋白(BSP)与维持性血液透析(MHD)患者腹主动脉钙化的关系。方法:选取2016年5月至2017年2月于本院血液净化中心规律透析患者75例。检测患者血清BSP,并进行腹部侧位X平片拍摄,根据kauppila半定量积分方法进行腹主动...目的:探讨血清骨唾液酸蛋白(BSP)与维持性血液透析(MHD)患者腹主动脉钙化的关系。方法:选取2016年5月至2017年2月于本院血液净化中心规律透析患者75例。检测患者血清BSP,并进行腹部侧位X平片拍摄,根据kauppila半定量积分方法进行腹主动脉钙化评分(AACs),参考CORD分段方法,根据AAC得分将患者分为无或轻度钙化组(AACs≤4)、中度钙化组(5≤AACs≤15)和重度钙化组(AACs≥16)。Logistic回归分析MHD患者AAC的影响因素。受试者工作特征(ROC)曲线分析BSP对血管钙化的诊断价值。结果:75例MHD患者中发生腹主动脉钙化者56例(74.67%),AACs中位数为4(0,24)分,血清BSP中位数为20.12(18.63,24.21)ng/ml。中度钙化组、重度钙化组BSP水平均高于无或轻度钙化组[22.43(19.58,6.84)ng/ml、21.99(19.87,26.18)ng/ml vs 19.16(17.3,23.3)ng/ml,P<0.05]。Logistic回归分析发现BSP是AAC的独立危险因素(OR=1.175,95%CI 1.004~1.375,P<0.05)。ROC曲线分析发现,BSP诊断AAC的曲线下面积为0.718(95%CI为0.604~0.833,P=0.001),BSP诊断AAC的临界值为21.51 ng/ml,灵敏度为0.711,特异度为0.595。结论:血清BSP水平和MHD患者AAC的严重程度相关,高水平的BSP是AAC的独立危险因素。BSP对MHD患者腹主动脉钙化具有潜在诊断价值。展开更多
In order to alleviate urban traffic congestion and provide fast vehicle paths,a hidden Markov model(HMM)based on multi-feature data of urban regional roads is constructed to solve the problems of low recognition rate ...In order to alleviate urban traffic congestion and provide fast vehicle paths,a hidden Markov model(HMM)based on multi-feature data of urban regional roads is constructed to solve the problems of low recognition rate and poor instability of traditional model algorithms.At first,the HHM is obtained by training.Then according to dynamic planning principle,the traffic states of intersections are obtained by the Viterbi algorithm.Finally,the optimal path is selected based on the obtained traffic states of intersections.The experiment results show that the proposed method is superior to other algorithms in road unobstruction rate and recognition rate under complex road conditions.展开更多
文摘目的:探讨血清骨唾液酸蛋白(BSP)与维持性血液透析(MHD)患者腹主动脉钙化的关系。方法:选取2016年5月至2017年2月于本院血液净化中心规律透析患者75例。检测患者血清BSP,并进行腹部侧位X平片拍摄,根据kauppila半定量积分方法进行腹主动脉钙化评分(AACs),参考CORD分段方法,根据AAC得分将患者分为无或轻度钙化组(AACs≤4)、中度钙化组(5≤AACs≤15)和重度钙化组(AACs≥16)。Logistic回归分析MHD患者AAC的影响因素。受试者工作特征(ROC)曲线分析BSP对血管钙化的诊断价值。结果:75例MHD患者中发生腹主动脉钙化者56例(74.67%),AACs中位数为4(0,24)分,血清BSP中位数为20.12(18.63,24.21)ng/ml。中度钙化组、重度钙化组BSP水平均高于无或轻度钙化组[22.43(19.58,6.84)ng/ml、21.99(19.87,26.18)ng/ml vs 19.16(17.3,23.3)ng/ml,P<0.05]。Logistic回归分析发现BSP是AAC的独立危险因素(OR=1.175,95%CI 1.004~1.375,P<0.05)。ROC曲线分析发现,BSP诊断AAC的曲线下面积为0.718(95%CI为0.604~0.833,P=0.001),BSP诊断AAC的临界值为21.51 ng/ml,灵敏度为0.711,特异度为0.595。结论:血清BSP水平和MHD患者AAC的严重程度相关,高水平的BSP是AAC的独立危险因素。BSP对MHD患者腹主动脉钙化具有潜在诊断价值。
基金Natural Science Foundation of Gansu Provincial Science&Technology Department(No.1504GKCA018)。
文摘In order to alleviate urban traffic congestion and provide fast vehicle paths,a hidden Markov model(HMM)based on multi-feature data of urban regional roads is constructed to solve the problems of low recognition rate and poor instability of traditional model algorithms.At first,the HHM is obtained by training.Then according to dynamic planning principle,the traffic states of intersections are obtained by the Viterbi algorithm.Finally,the optimal path is selected based on the obtained traffic states of intersections.The experiment results show that the proposed method is superior to other algorithms in road unobstruction rate and recognition rate under complex road conditions.
