Nosocomial or hospital acquired infections are a major challenge for low and middle income countries (LMICs) which have limited healthcare resources. Risk factors include the lack of appropriate hospital facilities su...Nosocomial or hospital acquired infections are a major challenge for low and middle income countries (LMICs) which have limited healthcare resources. Risk factors include the lack of appropriate hospital facilities such as isolation units, bed space, and sinks;inadequate waste management, contaminated equipment, inappropriate use of antibiotics and transmission of infection from the hands of healthcare workers and family caretakers due to inadequate hand washing. Nosocomial infections increase the costs of healthcare due to added antimicrobial treatment and prolonged hospitalization. Since the prevalence of nosocomial infections is generally higher in developing countries with limited resources, the socio-economic burden is even more severe in these countries. This review summarizes the current knowledge on the risks of hospital acquired infections and summarizes current recommendations for the development of hospital infrastructure and the institution of protocols to reduce these infections in LMICs such as Bangladesh.展开更多
The fertigation technique with raised bed planting for transplanted boro(winter,irrigated)rice production is a research focus nowadays.A field experiment compared two cultivation methods:the fertigation technique with...The fertigation technique with raised bed planting for transplanted boro(winter,irrigated)rice production is a research focus nowadays.A field experiment compared two cultivation methods:the fertigation technique within raised bed planting on boro rice,and fertilizer broadcasting in the conventional planting method.Compared to conventional fertilizer broadcasting,results showed that the new fertigation technique in raised bed planting increased grain yield of transplanted boro rice by up to 17.04%.It yielded a greater number of panicles per square meter,a greater number of grains per panicle,higher 1000-grains weight,and better plant growth attributes.Sterility percentage and weed infestation were lower.Thirty six percent of irrigation water and time for application could be saved.Water use efficiency for grain and biomass production was higher.The agronomic efficiency of nitrogen(N)fertilizer was significantly higher.This study concluded that fertigation in raised bed planting for transplanted boro rice is a new approach with higher yield and higher fertilizer and water use efficiency than the existing agronomic practice in Bangladesh.展开更多
A rigorous theoretical investigation is made of ion-acoustic shock structures in an unmagnetized three-component plasma whose constituents are nonextensive electrons, nonextensive positrons, and inertial ions. The Bur...A rigorous theoretical investigation is made of ion-acoustic shock structures in an unmagnetized three-component plasma whose constituents are nonextensive electrons, nonextensive positrons, and inertial ions. The Burgers equation is derived by employing the reductive perturbation method. The effects of electron and positron nonextensivity and ion kinematic viscosity on the properties of these ion-acoustic shock waves are briefly discussed. It is found that shock waves with positive and negative potentials are obtained to depend on the plasma parameters. The entailment of our results may be useful to understand some astrophysical and cosmological scenarios including stellar polytropes, hadronic matter and quark-gluon plasma, protoneutron stars, dark-matter halos, etc., where effects of nonextensivity can play significant roles.展开更多
The nonlinear propagation of ion-acoustic(IA) shock waves(SHWs) in a nonextensive multi-ion plasma system(consisting of inertial positive light ions as well as negative heavy ions, noninertial nonextensive electrons a...The nonlinear propagation of ion-acoustic(IA) shock waves(SHWs) in a nonextensive multi-ion plasma system(consisting of inertial positive light ions as well as negative heavy ions, noninertial nonextensive electrons and positrons) has been studied. The reductive perturbation technique has been employed to derive the Burgers equation.The basic properties(polarity, amplitude, width, etc.) of the IA SHWs are found to be significantly modified by the effects of nonextensivity of electrons and positrons, ion kinematic viscosity, temperature ratio of electrons and positrons, etc.It has been observed that SHWs with positive and negative potential are formed depending on the plasma parameters.The findings of our results obtained from this theoretical investigation may be useful in understanding the characteristics of IA SHWs both in laboratory and space plasmas.展开更多
Background: Post caesarean section (CS) wound infection or surgical site infection is a leading cause of prolonged hospital stay or readmission. An understanding of its risk factors is important. Methods: A case contr...Background: Post caesarean section (CS) wound infection or surgical site infection is a leading cause of prolonged hospital stay or readmission. An understanding of its risk factors is important. Methods: A case control study was conducted in the Department of Obstetrics and Gynecology of Sir Salimullah Medical College & Mitford Hospital, in Dhaka, Bangladesh from January to June 2014 to evaluate the risk factors of postoperative surgical site infection following CS. One hundred patients were studied. Results: Fifty patients of post CS wound infection (surgical site infection: SSI) were selected as cases. Body mass index > 25 (kg/m2), anemia (p = 0.001), prolonged rupture of membrane (p = 0.005), prolonged operation time (p = 0.019), and junior surgeons performing the operation (p = 0.011) were the risk factors for CS-SSI. Conclusions: Pre- and postoperative care and surgical training of junior doctors should be directed to these risk factors.展开更多
In developmental biology,knowledge of cell structure and their(morpho)dynamic behavior,leads to a comprehensive understanding of their conducts and the mechanisms in which they participate.This knowledge is a decisive...In developmental biology,knowledge of cell structure and their(morpho)dynamic behavior,leads to a comprehensive understanding of their conducts and the mechanisms in which they participate.This knowledge is a decisive factor in biological research and also in all drug development steps,medicinal or preventive therapies.Experimental cell analysis is hard,expensive,and time-consuming.To overcome these difficulties,in recent years,several computational object tracking methods,software system and packages have been developed in cell sciences that bring together different disciplines and branches of technologies.Object tracking is the process of locating and monitoring specific object and its behavior in sequential images.In this paper,a comprehensive review on object tracking stages and computational methods that are utilized in terms of cell tracking has been organized.Besides,the available software packages and toolkits,challenges,and their solution in time lapse microscopy images in this scope were reviewed.The aim of describing computational cell tracking methods and tools is that biologist and cell scientists might take advantage of these computational techniques to find another method to gain complementary information for their question of interest.展开更多
Pure ammonium diyidrogen phosphate and L-alanine doped ammonium diyidrogen phosphate crystals were grown from aqueous solutions by natural evaporation process. The grown crystals are characterized by Fourier Transform...Pure ammonium diyidrogen phosphate and L-alanine doped ammonium diyidrogen phosphate crystals were grown from aqueous solutions by natural evaporation process. The grown crystals are characterized by Fourier Transform Infrared spectroscopy, Energy Dispersive X-ray, UV-visible spectroscopy and differential thermal analysis. Crystal structure has been studied by powder X-ray diffraction. Pure and doped crystals both possessed tetragonal structure. The optical transparency is found to increase with the increase of doping concentration in the grown crystals and band gap energies of all crystals have been calculated at their cut off frequencies. It is found that the optical band gap increases with doping concentrations. D.C.electrical conductivity of grown crystals along the growth axis was carried out at temperatures ranging from 35-140°C by the conventional two-probe method. The conductivity of the crystals increases with temperature and also increases with the L-alanine concentration. The decomposition temperatures and weight loss have been estimated from the Thermo Gravimetric Analysis and Differential Thermal Analysis and hardness was found from the Vicker’s microhardness measurement.展开更多
BACKGROUND Diarrhoea is a frequent symptom in children with cancer, and occurs due to a composite effect of underlying disease and immunosuppression consequent to therapy, malnutrition, and non-infective aetiologies s...BACKGROUND Diarrhoea is a frequent symptom in children with cancer, and occurs due to a composite effect of underlying disease and immunosuppression consequent to therapy, malnutrition, and non-infective aetiologies such as mucositis. In a large proportion of cases, the aetiology of diarrhoea remains unknown but is often attributed to multiple pathogens including parasites.AIM To identify and describe the pathogens causing diarrhoea in Bangladeshi children with cancer.METHODS Two cross-sectional pilot studies were conducted involving paediatric oncology patients with diarrhoea. Stool samples were collected from children who were hospitalised with or without being treated with chemotherapy during the study period, and had diarrhoea at any stage during their admission. In the first study,stool samples were tested by conventional microbiological methods and by polymerase chain reaction for parasites, and by immunoassays for Clostridium difficile. In the second study, conventional microbiology was conducted for bacteria and parasites including an enzyme-linked immunosorbent assay for Cryptosporidium antigen, and in a subset, immunoassays for Clostridium difficile.RESULTS In the first study Giardia lamblia was detected in 68.5% of samples, Entamoeba histolytica in 13%, Cryptosporidium in 5.6%, non-toxigenic C. difficile in 22.4%, and other bacteria in 5.2%. In the second study, E. histolytica was detected in 10% of samples, Cryptosporidium in 4.3%, G. lamblia in 1.4%, C. difficile in 5.1%, and other bacteria in 5.7% of samples.CONCLUSION These pilot data suggest that parasites are important aetiologies of diarrhoea in Bangladeshi children with malignancy. While molecular diagnostic tools detect an array of stool pathogens with greater sensitivity, conventional diagnostic methods are also useful.展开更多
Objective:To document the clinical,biochemical and imaging phenotypes of immunocompetent patients with adrenal histoplasmosis.Methods:The clinical,biochemical and radiologic data of 18 immunocompetent patients[age:45....Objective:To document the clinical,biochemical and imaging phenotypes of immunocompetent patients with adrenal histoplasmosis.Methods:The clinical,biochemical and radiologic data of 18 immunocompetent patients[age:45.00(39.25,56.25)years,median(IQR),m/f(16/2)]with adrenal histoplasmosis presenting in the Department of Endocrinology,BSMMU between 2014 and 2020 were retrospectively analyzed.Results:All patients were seronegative for HIV infection,and 27.8%(5/18)had well controlled diabetes mellitus.The median duration of the symptoms was 6.00(IQR:4.00,11.25)months.All had significant weight loss,anorexia and weakness.Fever was present in 61.1%(11/18)patients and night sweat was present in 27.8%(5/18)cases.Hypotension and hyperpigmentation were present in 55.6%(10/18)and 66.7%(12/18)cases,respectively.Three of 18 patients presented with adrenal crisis.Hyponatremia occurred in 55.6%(10/18)cases,but none had hyperkalemia.Thirteen of 18 patients had adrenal insufficiency whereas 83.3%(15/18)had high adrenocorticotropic hormone.CT scan revealed bilateral adrenal enlargement in all cases with oval shape and regular margin.All were hypodense having radiodensity 21-90 hounsfield unit,and 11.1%(2/18)were heterogeneous in contrast enhancement.None had noticeable calcification whereas 1.1%(2/18)cases had central necrosis with peripheral rim enhancement.Hepatomegaly was present in 6 cases,splenomegaly in 3 cases and 5 patients had abdominal lymphadenopathy.Histoplasmosis were confirmed by positive fine needle aspiration cytology of adrenal tissue.Conclusions:Adrenal histoplasmosis should be considered in the list of differentials of bilateral adrenomegaly in immunocompetent individuals even living in non-endemic areas.展开更多
Pure potassium dihydrogen phosphate (KDP) crystals and KDP doped with L-alanine have been grown by slow evaporation technique at room temperature. Grown crystals have been characterized using powder X-ray diffraction,...Pure potassium dihydrogen phosphate (KDP) crystals and KDP doped with L-alanine have been grown by slow evaporation technique at room temperature. Grown crystals have been characterized using powder X-ray diffraction, (XRD), Energy Dispersive X-ray spectroscopy (EDX) and Fourier Transform Infrared spectroscopy (FTIR). The presence of L-alanine into pure KDP crystal was confirmed by FTIR and EDX spectra. Crystal structure has been studied by XRD. Pure KDP and L-alanine doped KDP crystals both possessed tetragonal structure. The transparency is found to increase with the increase of doping concentrations of the grown crystals as observed by UV-Vis spectra. A.C. electrical conductivity of grown crystals along the growth axis was carried out at various temperatures ranging from 35?C - 400?C. Dielectric constant and dielectric losses are measured as a function of temperature and this study reveals the contribution of space charge polarization. Crystal defects and surface morphology are studied by dissolution solvent technique and reveals the step growth mechanism for both pure and doped crystals.展开更多
文摘Nosocomial or hospital acquired infections are a major challenge for low and middle income countries (LMICs) which have limited healthcare resources. Risk factors include the lack of appropriate hospital facilities such as isolation units, bed space, and sinks;inadequate waste management, contaminated equipment, inappropriate use of antibiotics and transmission of infection from the hands of healthcare workers and family caretakers due to inadequate hand washing. Nosocomial infections increase the costs of healthcare due to added antimicrobial treatment and prolonged hospitalization. Since the prevalence of nosocomial infections is generally higher in developing countries with limited resources, the socio-economic burden is even more severe in these countries. This review summarizes the current knowledge on the risks of hospital acquired infections and summarizes current recommendations for the development of hospital infrastructure and the institution of protocols to reduce these infections in LMICs such as Bangladesh.
文摘The fertigation technique with raised bed planting for transplanted boro(winter,irrigated)rice production is a research focus nowadays.A field experiment compared two cultivation methods:the fertigation technique within raised bed planting on boro rice,and fertilizer broadcasting in the conventional planting method.Compared to conventional fertilizer broadcasting,results showed that the new fertigation technique in raised bed planting increased grain yield of transplanted boro rice by up to 17.04%.It yielded a greater number of panicles per square meter,a greater number of grains per panicle,higher 1000-grains weight,and better plant growth attributes.Sterility percentage and weed infestation were lower.Thirty six percent of irrigation water and time for application could be saved.Water use efficiency for grain and biomass production was higher.The agronomic efficiency of nitrogen(N)fertilizer was significantly higher.This study concluded that fertigation in raised bed planting for transplanted boro rice is a new approach with higher yield and higher fertilizer and water use efficiency than the existing agronomic practice in Bangladesh.
文摘A rigorous theoretical investigation is made of ion-acoustic shock structures in an unmagnetized three-component plasma whose constituents are nonextensive electrons, nonextensive positrons, and inertial ions. The Burgers equation is derived by employing the reductive perturbation method. The effects of electron and positron nonextensivity and ion kinematic viscosity on the properties of these ion-acoustic shock waves are briefly discussed. It is found that shock waves with positive and negative potentials are obtained to depend on the plasma parameters. The entailment of our results may be useful to understand some astrophysical and cosmological scenarios including stellar polytropes, hadronic matter and quark-gluon plasma, protoneutron stars, dark-matter halos, etc., where effects of nonextensivity can play significant roles.
文摘The nonlinear propagation of ion-acoustic(IA) shock waves(SHWs) in a nonextensive multi-ion plasma system(consisting of inertial positive light ions as well as negative heavy ions, noninertial nonextensive electrons and positrons) has been studied. The reductive perturbation technique has been employed to derive the Burgers equation.The basic properties(polarity, amplitude, width, etc.) of the IA SHWs are found to be significantly modified by the effects of nonextensivity of electrons and positrons, ion kinematic viscosity, temperature ratio of electrons and positrons, etc.It has been observed that SHWs with positive and negative potential are formed depending on the plasma parameters.The findings of our results obtained from this theoretical investigation may be useful in understanding the characteristics of IA SHWs both in laboratory and space plasmas.
文摘Background: Post caesarean section (CS) wound infection or surgical site infection is a leading cause of prolonged hospital stay or readmission. An understanding of its risk factors is important. Methods: A case control study was conducted in the Department of Obstetrics and Gynecology of Sir Salimullah Medical College & Mitford Hospital, in Dhaka, Bangladesh from January to June 2014 to evaluate the risk factors of postoperative surgical site infection following CS. One hundred patients were studied. Results: Fifty patients of post CS wound infection (surgical site infection: SSI) were selected as cases. Body mass index > 25 (kg/m2), anemia (p = 0.001), prolonged rupture of membrane (p = 0.005), prolonged operation time (p = 0.019), and junior surgeons performing the operation (p = 0.011) were the risk factors for CS-SSI. Conclusions: Pre- and postoperative care and surgical training of junior doctors should be directed to these risk factors.
文摘In developmental biology,knowledge of cell structure and their(morpho)dynamic behavior,leads to a comprehensive understanding of their conducts and the mechanisms in which they participate.This knowledge is a decisive factor in biological research and also in all drug development steps,medicinal or preventive therapies.Experimental cell analysis is hard,expensive,and time-consuming.To overcome these difficulties,in recent years,several computational object tracking methods,software system and packages have been developed in cell sciences that bring together different disciplines and branches of technologies.Object tracking is the process of locating and monitoring specific object and its behavior in sequential images.In this paper,a comprehensive review on object tracking stages and computational methods that are utilized in terms of cell tracking has been organized.Besides,the available software packages and toolkits,challenges,and their solution in time lapse microscopy images in this scope were reviewed.The aim of describing computational cell tracking methods and tools is that biologist and cell scientists might take advantage of these computational techniques to find another method to gain complementary information for their question of interest.
文摘Pure ammonium diyidrogen phosphate and L-alanine doped ammonium diyidrogen phosphate crystals were grown from aqueous solutions by natural evaporation process. The grown crystals are characterized by Fourier Transform Infrared spectroscopy, Energy Dispersive X-ray, UV-visible spectroscopy and differential thermal analysis. Crystal structure has been studied by powder X-ray diffraction. Pure and doped crystals both possessed tetragonal structure. The optical transparency is found to increase with the increase of doping concentration in the grown crystals and band gap energies of all crystals have been calculated at their cut off frequencies. It is found that the optical band gap increases with doping concentrations. D.C.electrical conductivity of grown crystals along the growth axis was carried out at temperatures ranging from 35-140°C by the conventional two-probe method. The conductivity of the crystals increases with temperature and also increases with the L-alanine concentration. The decomposition temperatures and weight loss have been estimated from the Thermo Gravimetric Analysis and Differential Thermal Analysis and hardness was found from the Vicker’s microhardness measurement.
文摘BACKGROUND Diarrhoea is a frequent symptom in children with cancer, and occurs due to a composite effect of underlying disease and immunosuppression consequent to therapy, malnutrition, and non-infective aetiologies such as mucositis. In a large proportion of cases, the aetiology of diarrhoea remains unknown but is often attributed to multiple pathogens including parasites.AIM To identify and describe the pathogens causing diarrhoea in Bangladeshi children with cancer.METHODS Two cross-sectional pilot studies were conducted involving paediatric oncology patients with diarrhoea. Stool samples were collected from children who were hospitalised with or without being treated with chemotherapy during the study period, and had diarrhoea at any stage during their admission. In the first study,stool samples were tested by conventional microbiological methods and by polymerase chain reaction for parasites, and by immunoassays for Clostridium difficile. In the second study, conventional microbiology was conducted for bacteria and parasites including an enzyme-linked immunosorbent assay for Cryptosporidium antigen, and in a subset, immunoassays for Clostridium difficile.RESULTS In the first study Giardia lamblia was detected in 68.5% of samples, Entamoeba histolytica in 13%, Cryptosporidium in 5.6%, non-toxigenic C. difficile in 22.4%, and other bacteria in 5.2%. In the second study, E. histolytica was detected in 10% of samples, Cryptosporidium in 4.3%, G. lamblia in 1.4%, C. difficile in 5.1%, and other bacteria in 5.7% of samples.CONCLUSION These pilot data suggest that parasites are important aetiologies of diarrhoea in Bangladeshi children with malignancy. While molecular diagnostic tools detect an array of stool pathogens with greater sensitivity, conventional diagnostic methods are also useful.
文摘Objective:To document the clinical,biochemical and imaging phenotypes of immunocompetent patients with adrenal histoplasmosis.Methods:The clinical,biochemical and radiologic data of 18 immunocompetent patients[age:45.00(39.25,56.25)years,median(IQR),m/f(16/2)]with adrenal histoplasmosis presenting in the Department of Endocrinology,BSMMU between 2014 and 2020 were retrospectively analyzed.Results:All patients were seronegative for HIV infection,and 27.8%(5/18)had well controlled diabetes mellitus.The median duration of the symptoms was 6.00(IQR:4.00,11.25)months.All had significant weight loss,anorexia and weakness.Fever was present in 61.1%(11/18)patients and night sweat was present in 27.8%(5/18)cases.Hypotension and hyperpigmentation were present in 55.6%(10/18)and 66.7%(12/18)cases,respectively.Three of 18 patients presented with adrenal crisis.Hyponatremia occurred in 55.6%(10/18)cases,but none had hyperkalemia.Thirteen of 18 patients had adrenal insufficiency whereas 83.3%(15/18)had high adrenocorticotropic hormone.CT scan revealed bilateral adrenal enlargement in all cases with oval shape and regular margin.All were hypodense having radiodensity 21-90 hounsfield unit,and 11.1%(2/18)were heterogeneous in contrast enhancement.None had noticeable calcification whereas 1.1%(2/18)cases had central necrosis with peripheral rim enhancement.Hepatomegaly was present in 6 cases,splenomegaly in 3 cases and 5 patients had abdominal lymphadenopathy.Histoplasmosis were confirmed by positive fine needle aspiration cytology of adrenal tissue.Conclusions:Adrenal histoplasmosis should be considered in the list of differentials of bilateral adrenomegaly in immunocompetent individuals even living in non-endemic areas.
文摘Pure potassium dihydrogen phosphate (KDP) crystals and KDP doped with L-alanine have been grown by slow evaporation technique at room temperature. Grown crystals have been characterized using powder X-ray diffraction, (XRD), Energy Dispersive X-ray spectroscopy (EDX) and Fourier Transform Infrared spectroscopy (FTIR). The presence of L-alanine into pure KDP crystal was confirmed by FTIR and EDX spectra. Crystal structure has been studied by XRD. Pure KDP and L-alanine doped KDP crystals both possessed tetragonal structure. The transparency is found to increase with the increase of doping concentrations of the grown crystals as observed by UV-Vis spectra. A.C. electrical conductivity of grown crystals along the growth axis was carried out at various temperatures ranging from 35?C - 400?C. Dielectric constant and dielectric losses are measured as a function of temperature and this study reveals the contribution of space charge polarization. Crystal defects and surface morphology are studied by dissolution solvent technique and reveals the step growth mechanism for both pure and doped crystals.
