Serum Bone Gla Protein (BGP) was observed in sera from entreated and treated within 6 months and more than 6 months patients with hyperthyroidism and hypothyroidism. Serum BGP in untreated hyperthyroidism and hypothyr...Serum Bone Gla Protein (BGP) was observed in sera from entreated and treated within 6 months and more than 6 months patients with hyperthyroidism and hypothyroidism. Serum BGP in untreated hyperthyroidism and hypothyroidism were 21. 2±2. 8 and 3. 8±0.5μg/L respectively,which were significantly different from those of normal control (all, P<0. 001). Serum T3 and T4 of treated Patients with hyperthyroidism within 6 months had normalized, but serum BGP was still higher than the normal one. Serum BGP returned to normal in treated patients with hyperthyroidism more than 6 months. We consider serum BGP is a sensitive marker of hyperthyroid osteopathy and besides thyroxine, there are also some unknown factors that participate in serum BGP secretion,which is worthy to be further investigated.展开更多
文摘Serum Bone Gla Protein (BGP) was observed in sera from entreated and treated within 6 months and more than 6 months patients with hyperthyroidism and hypothyroidism. Serum BGP in untreated hyperthyroidism and hypothyroidism were 21. 2±2. 8 and 3. 8±0.5μg/L respectively,which were significantly different from those of normal control (all, P<0. 001). Serum T3 and T4 of treated Patients with hyperthyroidism within 6 months had normalized, but serum BGP was still higher than the normal one. Serum BGP returned to normal in treated patients with hyperthyroidism more than 6 months. We consider serum BGP is a sensitive marker of hyperthyroid osteopathy and besides thyroxine, there are also some unknown factors that participate in serum BGP secretion,which is worthy to be further investigated.
