An amphiphilic polymer bearing tetraphenylethene (TPE) moiety was synthesized by convenient reactions. The polymer exhibits unique aggregation-induced emission (AIE) characteristics and can self-assemble to size-tunab...An amphiphilic polymer bearing tetraphenylethene (TPE) moiety was synthesized by convenient reactions. The polymer exhibits unique aggregation-induced emission (AIE) characteristics and can self-assemble to size-tunable particles in DMF/water mixtures. The polymer nanoparticles can be used for cell imaging, which provides a potential stable fluorescent tool to monitor the distribution of drugs and bioconjugates in living cells.展开更多
The micelles behavior of amphiphilic block copolymer P（Styrene\|b\|acrylic acid）, in aqueous solvent was studied by dynamic light scattering and TEM techniques. The diameters of micelle decreased and then increased ...The micelles behavior of amphiphilic block copolymer P（Styrene\|b\|acrylic acid）, in aqueous solvent was studied by dynamic light scattering and TEM techniques. The diameters of micelle decreased and then increased with the decrease of the pH of the solution, and the similar phenomenon was also detected with the increase of the concentration of the calcium ion. Without added acid, the micelles were small spheres of low polydispersity with an average diameter 48 nm. When the value of pH was less than 2, the micelles were unstable. It was found that the Ca\+\{2+\} was linked with the carboxyl in the same micelle when the concentration of the CaCl\-2 was less than 0\^2 mg/mL. The diameter of micelle was smaller than the one without Ca\+\{2+\}. The Ca\+\{2+\} was linked with the carboxyl between the different micelles when the concentration of the CaCl\-2 was more than 0\^5 mg/mL and the micelle was unstable. The diameters of micelles（from 37 nm to 100 nm） can be controlled by adding an appropriate concentration of CaCl\-2 between 0\^2\0\^5 mg/mL.展开更多
Three well-defined diblock copolymers ofpoly（methyl methacrylate-b-methacrylic acid） （P（MMA-b-MAA）） were synthesized using atom transfer radical polymerization method and varying poly（methacrylic acid） （PMAA...Three well-defined diblock copolymers ofpoly（methyl methacrylate-b-methacrylic acid） （P（MMA-b-MAA）） were synthesized using atom transfer radical polymerization method and varying poly（methacrylic acid） （PMAA） chain lengths. These copolymers were blended with PVC to fabricate porous membranes via phase inversion process. Membrane morphologies were observed by scanning electron microscopy （SEM）, and chemical composition changes of the membrane surfaces were measured by X-ray photoelectron spectroscopy （XPS）. Static and dynamic protein adsorption experiments were used to evaluate antifouling properties of the blend membranes. It was found that, the blend membranes containing longer PMAA arm length showed lower static protein adsorption, higher water permeation flux and better protein solution flux recovery.展开更多
以三硫代碳酸(α,α′-二甲基α-″-乙酸)酯为链转移剂,苯乙烯为第一单体,通过RAFT聚合技术合成出大分子链转移剂(PS-CTA);以甲基丙烯酸-N,N-二甲氨基乙酯为第二共聚单体合成出具有不同链长的三嵌段聚合物。GPC对PS-CTA的表征表明:PS-CT...以三硫代碳酸(α,α′-二甲基α-″-乙酸)酯为链转移剂,苯乙烯为第一单体,通过RAFT聚合技术合成出大分子链转移剂(PS-CTA);以甲基丙烯酸-N,N-二甲氨基乙酯为第二共聚单体合成出具有不同链长的三嵌段聚合物。GPC对PS-CTA的表征表明:PS-CTA的分子量分别为2100、3500和5000g/m o l,分子量分布约为1.03;NM R表征确定了三嵌段共聚物的结构。三嵌段共聚物在选择性溶剂中可自组装成胶束,通过TEM观察发现胶束呈球形;并且胶束的尺寸随嵌段共聚物分子量的增加而增加。展开更多
基金supported by the National Natural Science Foundation of China (20974028, 20974098, and 21174120)the National Basic Research Program of China (2009CB623605)+1 种基金the Research Grants Council of Hong Kong (603509, HKUST2/CRF/10, 604711, and N_HKUST620/11)B.Z.T. thanks the support from the Cao Guangbiao Foundation of Zhejiang University
文摘An amphiphilic polymer bearing tetraphenylethene (TPE) moiety was synthesized by convenient reactions. The polymer exhibits unique aggregation-induced emission (AIE) characteristics and can self-assemble to size-tunable particles in DMF/water mixtures. The polymer nanoparticles can be used for cell imaging, which provides a potential stable fluorescent tool to monitor the distribution of drugs and bioconjugates in living cells.
文摘The micelles behavior of amphiphilic block copolymer P（Styrene\|b\|acrylic acid）, in aqueous solvent was studied by dynamic light scattering and TEM techniques. The diameters of micelle decreased and then increased with the decrease of the pH of the solution, and the similar phenomenon was also detected with the increase of the concentration of the calcium ion. Without added acid, the micelles were small spheres of low polydispersity with an average diameter 48 nm. When the value of pH was less than 2, the micelles were unstable. It was found that the Ca\+\{2+\} was linked with the carboxyl in the same micelle when the concentration of the CaCl\-2 was less than 0\^2 mg/mL. The diameter of micelle was smaller than the one without Ca\+\{2+\}. The Ca\+\{2+\} was linked with the carboxyl between the different micelles when the concentration of the CaCl\-2 was more than 0\^5 mg/mL and the micelle was unstable. The diameters of micelles（from 37 nm to 100 nm） can be controlled by adding an appropriate concentration of CaCl\-2 between 0\^2\0\^5 mg/mL.
基金supported by the National 973 Program(No.2009CB623402)the National Natural Science Foundation of China(No.20974094)
文摘Three well-defined diblock copolymers ofpoly（methyl methacrylate-b-methacrylic acid） （P（MMA-b-MAA）） were synthesized using atom transfer radical polymerization method and varying poly（methacrylic acid） （PMAA） chain lengths. These copolymers were blended with PVC to fabricate porous membranes via phase inversion process. Membrane morphologies were observed by scanning electron microscopy （SEM）, and chemical composition changes of the membrane surfaces were measured by X-ray photoelectron spectroscopy （XPS）. Static and dynamic protein adsorption experiments were used to evaluate antifouling properties of the blend membranes. It was found that, the blend membranes containing longer PMAA arm length showed lower static protein adsorption, higher water permeation flux and better protein solution flux recovery.
文摘以三硫代碳酸(α,α′-二甲基α-″-乙酸)酯为链转移剂,苯乙烯为第一单体,通过RAFT聚合技术合成出大分子链转移剂(PS-CTA);以甲基丙烯酸-N,N-二甲氨基乙酯为第二共聚单体合成出具有不同链长的三嵌段聚合物。GPC对PS-CTA的表征表明:PS-CTA的分子量分别为2100、3500和5000g/m o l,分子量分布约为1.03;NM R表征确定了三嵌段共聚物的结构。三嵌段共聚物在选择性溶剂中可自组装成胶束,通过TEM观察发现胶束呈球形;并且胶束的尺寸随嵌段共聚物分子量的增加而增加。
