目的:分析成人双颌前突患者治疗前后上颌切牙区唇腭侧牙槽骨的变化,为正畸治疗中在牙槽骨内的安全移动牙齿提供参考依据。方法:纳入23例成人双颌前突的患者,拔除4颗第一前磨牙,采用直丝弓矫治技术一步法整体内收上下前牙。患者治疗前后...目的:分析成人双颌前突患者治疗前后上颌切牙区唇腭侧牙槽骨的变化,为正畸治疗中在牙槽骨内的安全移动牙齿提供参考依据。方法:纳入23例成人双颌前突的患者,拔除4颗第一前磨牙,采用直丝弓矫治技术一步法整体内收上下前牙。患者治疗前后均拍摄锥体束CT片,测量上颌切牙区唇腭侧牙槽骨厚度(alveolar bone thickness,ABT)、釉牙骨质界-牙槽嵴顶的高度(alveolar bone height,ABH)和牙槽骨面积(alveolar bone area,ABA)。结果:治疗后上颌切牙区唇侧的ABT在根中和根尖部水平显著升高,而腭侧的ABT在颈部、根中和根尖3个水平上均下降(P<0.05);中切牙在颈部和根中两个水平上总ABT显著减少(P<0.05),而侧切牙在颈部、根中和根尖处总ABT均减少(P<0.05);正畸治疗后,切牙区腭侧ABA减少,而唇侧ABA增加(P<0.05);上颌中切牙和侧切牙腭侧的ABH和上颌侧切牙唇侧的ABH显著增加(P<0.01)。结论:正畸治疗会导致成人双颌前突患者的切牙区腭侧的牙槽骨发生显著吸收,减少整个切牙区的牙槽骨量,需关注其对牙周组织的长期影响。展开更多
Objective:To investigate effect of orthodontic force on inflammatory periodontal tissue remodeling and expression of IL-6 and IL-8 in rats.Methods:Eighty SD rats were randomly divided into 4 groups,blank control group...Objective:To investigate effect of orthodontic force on inflammatory periodontal tissue remodeling and expression of IL-6 and IL-8 in rats.Methods:Eighty SD rats were randomly divided into 4 groups,blank control group(group A)with 5 rats,treatment normal group(group B)with 25 rats,inflammation control group(group(group C)with 25 rats,inflammation treatment group(group D)with 25 rats.Immunohistochemistry and histomorphometric analysis was performed to measure the expression of IL-6,IL-8 and the firet molar to the recent movement in the distance.Results:The expression of IL-8 reached a maximum on day 5 and declined thereafter in group B;the expression of IL-6 reached a maximum on day 5 in group B.The expression of IL-6 and IL-8 was gradually weakened with time in group C.The expression of IL-6 and IL-8 were high,and reached a maximum on day 5 and declined thereafter in group D.AD of positive cells in group D were higher than group B at each time point(P<0.05).The time which 0.49 N orthodontic force was loaded was longer,orthodontic tooth movement distance was greater.Movement distance in group D were longer than group B(P<0.05).Conclusions:Orthodontic force as well as inflammatory stimulus can evoke the expression of IL-6 and IL-8.Under the combined effects of inflammation and orthodontic force,the expression of IL-6,IL-8will increase.展开更多
文摘目的:分析成人双颌前突患者治疗前后上颌切牙区唇腭侧牙槽骨的变化,为正畸治疗中在牙槽骨内的安全移动牙齿提供参考依据。方法:纳入23例成人双颌前突的患者,拔除4颗第一前磨牙,采用直丝弓矫治技术一步法整体内收上下前牙。患者治疗前后均拍摄锥体束CT片,测量上颌切牙区唇腭侧牙槽骨厚度(alveolar bone thickness,ABT)、釉牙骨质界-牙槽嵴顶的高度(alveolar bone height,ABH)和牙槽骨面积(alveolar bone area,ABA)。结果:治疗后上颌切牙区唇侧的ABT在根中和根尖部水平显著升高,而腭侧的ABT在颈部、根中和根尖3个水平上均下降(P<0.05);中切牙在颈部和根中两个水平上总ABT显著减少(P<0.05),而侧切牙在颈部、根中和根尖处总ABT均减少(P<0.05);正畸治疗后,切牙区腭侧ABA减少,而唇侧ABA增加(P<0.05);上颌中切牙和侧切牙腭侧的ABH和上颌侧切牙唇侧的ABH显著增加(P<0.01)。结论:正畸治疗会导致成人双颌前突患者的切牙区腭侧的牙槽骨发生显著吸收,减少整个切牙区的牙槽骨量,需关注其对牙周组织的长期影响。
基金supported by Department of Science and Technology in Henan Province(No 122300410407)
文摘Objective:To investigate effect of orthodontic force on inflammatory periodontal tissue remodeling and expression of IL-6 and IL-8 in rats.Methods:Eighty SD rats were randomly divided into 4 groups,blank control group(group A)with 5 rats,treatment normal group(group B)with 25 rats,inflammation control group(group(group C)with 25 rats,inflammation treatment group(group D)with 25 rats.Immunohistochemistry and histomorphometric analysis was performed to measure the expression of IL-6,IL-8 and the firet molar to the recent movement in the distance.Results:The expression of IL-8 reached a maximum on day 5 and declined thereafter in group B;the expression of IL-6 reached a maximum on day 5 in group B.The expression of IL-6 and IL-8 was gradually weakened with time in group C.The expression of IL-6 and IL-8 were high,and reached a maximum on day 5 and declined thereafter in group D.AD of positive cells in group D were higher than group B at each time point(P<0.05).The time which 0.49 N orthodontic force was loaded was longer,orthodontic tooth movement distance was greater.Movement distance in group D were longer than group B(P<0.05).Conclusions:Orthodontic force as well as inflammatory stimulus can evoke the expression of IL-6 and IL-8.Under the combined effects of inflammation and orthodontic force,the expression of IL-6,IL-8will increase.
