AIM: To evaluate the efficacy of sequential blood purification therapy in the treatment of critical patients with hyperlipidemic severe acute pancreatitis.METHODS: Thirty-one intensive care unit(ICU) patients with hyp...AIM: To evaluate the efficacy of sequential blood purification therapy in the treatment of critical patients with hyperlipidemic severe acute pancreatitis.METHODS: Thirty-one intensive care unit(ICU) patients with hyperlipidemic severe acute pancreatitis treated at the Second Affiliated Hospital of Harbin Medical University were divided into either a study group(n = 15; July 1, 2012 to June 30, 2014) or a control group(n = 16; July 1, 2010 to June 30, 2012) based on the implementation of sequential blood purification therapy. The control group received continuous venous-venous hemofiltration(CVVH) on the basis of conventional treatments, and the therapeutic dose of CVVH was 30 m L/kg per hour. The study group received sequential plasma exchange and CVVH on the basis of conventional treatments. The anticoagulation regimen of CVVH is the regional citrate anticoagulation. Mortality rate on day 28, rates of systemic and local complications, duration of ICU, and time to target serum lipid level, as well as physiologic and laboratory indices were compared between the two groups.RESULTS: The mortality rate on day 28 was significantly lower in the study group than in the control group(13.33% vs 37.50%; P < 0.05). The duration of ICU stay was significantly shorter in the study group than in the control group(7.4 ± 1.35 d vs 9.19 ± 2.99 d, P < 0.05). The time to target serum lipid level was significantly shorter in the study group than in the control group(3.47 ± 0.52 d vs 7.90 ± 1.14 d, P < 0.01). There were no significant differences in the rates of systemic complications and local complications between the two groups(60% vs 50% and 80% vs 81%, respectively). In the comparisons of physiologic and laboratory indices, serum albumin and C-reactive protein were significantly better in the study group than in the control group after treatment(37.8 ± 4.6 g/L vs 38.9 ± 5.7 g/L, and 20.5 ± 6.4 mg/L vs 28.5 ± 7.1 mg/L, respectively, both P < 0.05). With the exception of plateletcrit, no other indices showed significant di展开更多
BACKGROUND： Plasma exchange （PE）-centered artificial liver support system reduced the high mortality rate of hepa titis B virus （HBV）-related acute-on-chronic liver failure （ACLF）. But the data were diverse in ...BACKGROUND： Plasma exchange （PE）-centered artificial liver support system reduced the high mortality rate of hepa titis B virus （HBV）-related acute-on-chronic liver failure （ACLF）. But the data were diverse in different medical centers. The present prospective nationwide study was to evaluate the effects of PE on patients with HBV-ACLF at different stages.展开更多
Soil acidification is an important process in land degradation around the world as well as in China.Acidification of Alfisols was investigated in the tea gardens with various years of tea cultivation in the eastern Ch...Soil acidification is an important process in land degradation around the world as well as in China.Acidification of Alfisols was investigated in the tea gardens with various years of tea cultivation in the eastern China.Cultivation of tea plants caused soil acidification and soil acidity increased with the increase of tea cultivation period.Soil pH of composite samples from cultivated layers decreased by 1.37,1.62 and 1.85,respectively,after 13,34 and 54 years of tea plantation,as compared to the surface soil obtained from the unused land.Soil acidification rates at early stages of tea cultivation were found to be higher than those at the later stages.The acidification rate for the period of 0-13 years was as high as 4.40 kmol H + ha ?1 year ?1 for the cultivated layer samples.Soil acidification induced the decrease of soil exchangeable base cations and base cation saturation and thus increased the soil exchangeable acidity.Soil acidification also caused the decrease of soil cation exchange capacity,especially for the 54-year-old tea garden.Soil acidification induced by tea plantation also led to the increase of soil exchangeable Al and soluble Al,which was responsible for the Al toxicity to plants.展开更多
An analysis of historical oxygen data provides evidence on the water exchange between theSouth China Sea (SCS) and the Pacific Ocean (PO). In the vicinity of the Luzon Strait (LS) , the dissolved oxygen concentration ...An analysis of historical oxygen data provides evidence on the water exchange between theSouth China Sea (SCS) and the Pacific Ocean (PO). In the vicinity of the Luzon Strait (LS) , the dissolved oxygen concentration of sea water is found to be lower on the Pacific side than on the SCS side at depths between 700 and 1500 m (intermediate layer) , while the situation is reversed above 700 m (upper layer) and below 1 500 m (deep layer). The evidence suggests that water exits the SCS in the intermediate layer but enters it from the Pacific in both the upper and the deep layers, supporting the earlier speculation that the Luzon Strait transport has a sandwiched structure in the vertical. Within the SCS basin, the oxygen distribution indicates widespread vertical movement, including the upwelling in the intermediate layer and the downwelling in the deep layer.展开更多
In order to examine the effects of the decrease of future precipitation on the eco-physiological characteristics of sea buckthorn (Hippophae rhamnoides Linn.) in Huangfuchuan Watershed in Nei Mongol, a water gradient ...In order to examine the effects of the decrease of future precipitation on the eco-physiological characteristics of sea buckthorn (Hippophae rhamnoides Linn.) in Huangfuchuan Watershed in Nei Mongol, a water gradient experiment was conducted based on the four specially designed water supply levels, including normal precipitation, slight drought, drought and extreme drought. Results of ANOVE showed that different water gradients had a significant effect on (1) microhabitat factors, such as soil water content and soil temperature; (2) gas exchange, such as net photosynthetic rate, stomatal conductance and transpiration rate; (3) resource use efficiency; and (4) leaf water potential. Water use efficiency of H rhamnoides could increase under moderate water stress, i.e. drought condition, while its net photosynthetic rate and transpiration rate decreased. All kinds of eco-physiological characteristics proved H. rhamnoides seedlings under all water supplies were affected by water stress more or less and that mechanism of intrinsic physiological regulation in seedlings under the extreme drought conditions had the appearance of turbulence to a certain extent. Therefore, H rhamnoides seedlings in Huangfuchuan Watershed could not acclimate to extreme drought conditions.展开更多
基金Supported by Natural Science Foundation of Heilongjiang Province,China
文摘AIM: To evaluate the efficacy of sequential blood purification therapy in the treatment of critical patients with hyperlipidemic severe acute pancreatitis.METHODS: Thirty-one intensive care unit(ICU) patients with hyperlipidemic severe acute pancreatitis treated at the Second Affiliated Hospital of Harbin Medical University were divided into either a study group(n = 15; July 1, 2012 to June 30, 2014) or a control group(n = 16; July 1, 2010 to June 30, 2012) based on the implementation of sequential blood purification therapy. The control group received continuous venous-venous hemofiltration(CVVH) on the basis of conventional treatments, and the therapeutic dose of CVVH was 30 m L/kg per hour. The study group received sequential plasma exchange and CVVH on the basis of conventional treatments. The anticoagulation regimen of CVVH is the regional citrate anticoagulation. Mortality rate on day 28, rates of systemic and local complications, duration of ICU, and time to target serum lipid level, as well as physiologic and laboratory indices were compared between the two groups.RESULTS: The mortality rate on day 28 was significantly lower in the study group than in the control group(13.33% vs 37.50%; P < 0.05). The duration of ICU stay was significantly shorter in the study group than in the control group(7.4 ± 1.35 d vs 9.19 ± 2.99 d, P < 0.05). The time to target serum lipid level was significantly shorter in the study group than in the control group(3.47 ± 0.52 d vs 7.90 ± 1.14 d, P < 0.01). There were no significant differences in the rates of systemic complications and local complications between the two groups(60% vs 50% and 80% vs 81%, respectively). In the comparisons of physiologic and laboratory indices, serum albumin and C-reactive protein were significantly better in the study group than in the control group after treatment(37.8 ± 4.6 g/L vs 38.9 ± 5.7 g/L, and 20.5 ± 6.4 mg/L vs 28.5 ± 7.1 mg/L, respectively, both P < 0.05). With the exception of plateletcrit, no other indices showed significant di
基金supported by grants from the National Science and Technology Major Project(2012ZX10002004)Scientific Research Fund of Zhejiang Provincial Education Department(Y201328037)the opening foundation of the State Key Laboratory for Diagnosis and Treatment of Infectious Diseases and Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,First Affiliated Hospital,Zhejiang University School of Medicine(2015KF04)
文摘BACKGROUND： Plasma exchange （PE）-centered artificial liver support system reduced the high mortality rate of hepa titis B virus （HBV）-related acute-on-chronic liver failure （ACLF）. But the data were diverse in different medical centers. The present prospective nationwide study was to evaluate the effects of PE on patients with HBV-ACLF at different stages.
基金Supported by the National Nature Science Foundation of China (No. 30872009)the Earmarked Fund for Modern Agro-Industry Technology Research System of China (No. nycytx-23)
文摘Soil acidification is an important process in land degradation around the world as well as in China.Acidification of Alfisols was investigated in the tea gardens with various years of tea cultivation in the eastern China.Cultivation of tea plants caused soil acidification and soil acidity increased with the increase of tea cultivation period.Soil pH of composite samples from cultivated layers decreased by 1.37,1.62 and 1.85,respectively,after 13,34 and 54 years of tea plantation,as compared to the surface soil obtained from the unused land.Soil acidification rates at early stages of tea cultivation were found to be higher than those at the later stages.The acidification rate for the period of 0-13 years was as high as 4.40 kmol H + ha ?1 year ?1 for the cultivated layer samples.Soil acidification induced the decrease of soil exchangeable base cations and base cation saturation and thus increased the soil exchangeable acidity.Soil acidification also caused the decrease of soil cation exchange capacity,especially for the 54-year-old tea garden.Soil acidification induced by tea plantation also led to the increase of soil exchangeable Al and soluble Al,which was responsible for the Al toxicity to plants.
基金This research was funded by Frontier Research System for Global Change through its sponsorship of the International Pacific Research Center (IPRC) and by the U. S. National Science Foundation under contract Grant No. OCEOO - 95906.
文摘An analysis of historical oxygen data provides evidence on the water exchange between theSouth China Sea (SCS) and the Pacific Ocean (PO). In the vicinity of the Luzon Strait (LS) , the dissolved oxygen concentration of sea water is found to be lower on the Pacific side than on the SCS side at depths between 700 and 1500 m (intermediate layer) , while the situation is reversed above 700 m (upper layer) and below 1 500 m (deep layer). The evidence suggests that water exits the SCS in the intermediate layer but enters it from the Pacific in both the upper and the deep layers, supporting the earlier speculation that the Luzon Strait transport has a sandwiched structure in the vertical. Within the SCS basin, the oxygen distribution indicates widespread vertical movement, including the upwelling in the intermediate layer and the downwelling in the deep layer.
文摘In order to examine the effects of the decrease of future precipitation on the eco-physiological characteristics of sea buckthorn (Hippophae rhamnoides Linn.) in Huangfuchuan Watershed in Nei Mongol, a water gradient experiment was conducted based on the four specially designed water supply levels, including normal precipitation, slight drought, drought and extreme drought. Results of ANOVE showed that different water gradients had a significant effect on (1) microhabitat factors, such as soil water content and soil temperature; (2) gas exchange, such as net photosynthetic rate, stomatal conductance and transpiration rate; (3) resource use efficiency; and (4) leaf water potential. Water use efficiency of H rhamnoides could increase under moderate water stress, i.e. drought condition, while its net photosynthetic rate and transpiration rate decreased. All kinds of eco-physiological characteristics proved H. rhamnoides seedlings under all water supplies were affected by water stress more or less and that mechanism of intrinsic physiological regulation in seedlings under the extreme drought conditions had the appearance of turbulence to a certain extent. Therefore, H rhamnoides seedlings in Huangfuchuan Watershed could not acclimate to extreme drought conditions.
