目的 研究中国布依族、苗族人群线粒体 DNA Region V区的遗传多态性。方法 采用 PCR直接测序法对布依族 (96份 )及苗族人 (90份 )样本线粒体 DNA Region V区进行序列分析。结果 在布依族及苗族样本中只发现标准型和短型两种多态 ,短...目的 研究中国布依族、苗族人群线粒体 DNA Region V区的遗传多态性。方法 采用 PCR直接测序法对布依族 (96份 )及苗族人 (90份 )样本线粒体 DNA Region V区进行序列分析。结果 在布依族及苗族样本中只发现标准型和短型两种多态 ,短型多态 (即 9bp缺失 )频率在布依族、苗族人群中分别为31.1%和 33.3%。结论 中国布依族、苗族人群线粒体 DNA Region V区有相似的多态性 ,而与其他民族或人种有一定差异。展开更多
We investigated the distribution of Y-chromosome haplotype using 19 Y-SNPs in Han Chinese populations from 22 provinces of China. Our data indicate distinctive patterns of Y chromosome between southern and northern Ha...We investigated the distribution of Y-chromosome haplotype using 19 Y-SNPs in Han Chinese populations from 22 provinces of China. Our data indicate distinctive patterns of Y chromosome between southern and northern Han Chinese populations. The southern populations are much more polymorphic than northern populations. The latter has only a subset of the southern haplotypes. This result confirms the genetic difference observed between southern and northern ethnic populations in East Asia. It supports the hypothesis that the first settlement of modern hu-mans of African origin occurred in the southern part of East Asia during the last Ice Age, and a northward migration led to the peopling of northern China.展开更多
文摘目的 研究中国布依族、苗族人群线粒体 DNA Region V区的遗传多态性。方法 采用 PCR直接测序法对布依族 (96份 )及苗族人 (90份 )样本线粒体 DNA Region V区进行序列分析。结果 在布依族及苗族样本中只发现标准型和短型两种多态 ,短型多态 (即 9bp缺失 )频率在布依族、苗族人群中分别为31.1%和 33.3%。结论 中国布依族、苗族人群线粒体 DNA Region V区有相似的多态性 ,而与其他民族或人种有一定差异。
基金the National Natural Science Foundation of China (Grant No. 39993420).
文摘We investigated the distribution of Y-chromosome haplotype using 19 Y-SNPs in Han Chinese populations from 22 provinces of China. Our data indicate distinctive patterns of Y chromosome between southern and northern Han Chinese populations. The southern populations are much more polymorphic than northern populations. The latter has only a subset of the southern haplotypes. This result confirms the genetic difference observed between southern and northern ethnic populations in East Asia. It supports the hypothesis that the first settlement of modern hu-mans of African origin occurred in the southern part of East Asia during the last Ice Age, and a northward migration led to the peopling of northern China.
