来源于中胚层的骨髓间充质干细胞(BMSCs),能够进行自我更新,从而实现多种不同的发育方式。由于其易于体外扩增和外源基因导入等优点,在骨缺损修复中具有广阔的应用前景。近年来,随着组织工程学理论和技术的不断进步,将BMSCs应用于颌骨...来源于中胚层的骨髓间充质干细胞(BMSCs),能够进行自我更新,从而实现多种不同的发育方式。由于其易于体外扩增和外源基因导入等优点,在骨缺损修复中具有广阔的应用前景。近年来,随着组织工程学理论和技术的不断进步,将BMSCs应用于颌骨缺损修复中取得了卓越的成果,改善了颌骨缺损的治愈效果。基于此,本文对骨髓间充质干细胞在口腔医学领域的应用和疗效作一综述,以期为临床医生提供更加科学的理论依据。Bone marrow mesenchymal stem cells (BMSCs) deriving from the mesoderm can self-renew and achieve a variety of different development modes. Because of its advantages of easy in vitro expansion and foreign gene introduction, it has a broad application prospect in bone defect repair. In recent years, with the continuous progress of tissue engineering theory and technology, the application of BMSCs in jaw defect repair has achieved excellent results and improved the healing effect of jaw defect. Based on this, this paper reviews the application and efficacy of bone marrow mesenchymal stem cells in stomatology, in order to provide more scientific theoretical basis for clinicians.展开更多
文摘来源于中胚层的骨髓间充质干细胞(BMSCs),能够进行自我更新,从而实现多种不同的发育方式。由于其易于体外扩增和外源基因导入等优点,在骨缺损修复中具有广阔的应用前景。近年来,随着组织工程学理论和技术的不断进步,将BMSCs应用于颌骨缺损修复中取得了卓越的成果,改善了颌骨缺损的治愈效果。基于此,本文对骨髓间充质干细胞在口腔医学领域的应用和疗效作一综述,以期为临床医生提供更加科学的理论依据。Bone marrow mesenchymal stem cells (BMSCs) deriving from the mesoderm can self-renew and achieve a variety of different development modes. Because of its advantages of easy in vitro expansion and foreign gene introduction, it has a broad application prospect in bone defect repair. In recent years, with the continuous progress of tissue engineering theory and technology, the application of BMSCs in jaw defect repair has achieved excellent results and improved the healing effect of jaw defect. Based on this, this paper reviews the application and efficacy of bone marrow mesenchymal stem cells in stomatology, in order to provide more scientific theoretical basis for clinicians.
