摘要
抗原概念是相对概念,其中狭义的抗原概念高度凝练了适应性免疫应答激活及再次识别相同抗原的过程,揭示了疫苗的保护作用机制,对于指导疫苗研发具有重要意义。但狭义的抗原概念涉及适应性免疫系统成员B细胞、T细胞及其效应产物,初学者难理解其内在含义;且抗原分类是免疫应答过程的高度总结,多种分类方式加大了本章节的学习难度。本教学团队针对抗原章节中存在的教学难点深入剖析,实施了以抗体结构和功能为突破点、简化的适应性免疫应答过程为教学逻辑核心的策略,形成了贯穿抗原章节主要内容的思维导图,有效地提高了课堂教学效果。
The concept of“antigen”is a relative one.The narrow concept of it condenses the process of activation of adaptive immune response and re-recognition of the same antigen,revealing the protective mechanism of vaccines with great significance for research and development of vaccines.However,the narrow concept involves adaptive immune system members:B cells,T cells and their effector products,which is dificult for beginners to understand the inherent meaning.Meanwhile,antigen classification fully summarizes the immune response process,so a variety of classification approach increases the difficulty in learning.Our teaching team analyzes the difficulties of this chapter in depth,and we implements the strategy that takes antibody structure and function as the breakthrough point and simplified adaptive immune response process as the core in teaching.A mind map that includes the main contents of this chapter is made during the process,which promotes the effectiveness of classroom teaching greatly.
作者
唐康
王微
张瑞
张宇丝
张春梅
庄然
张赟
陈丽华
马樱
TANG Kang;WANG Wei;ZHANG Rui;ZHANG Yusi;ZHANG Chunmei;ZHUANG Ran;ZHANG Yun;CHEN Lihua;MA Ying(Department of Immunology,School of Basic Medicine,Air Force Medical University,Xi'an 710032,China)
出处
《细胞与分子免疫学杂志》
CAS
CSCD
北大核心
2023年第6期571-574,共4页
Chinese Journal of Cellular and Molecular Immunology
基金
国家自然科学基金青年项目(81901600)。
关键词
抗原
相对概念
免疫应答
抗原分类
思维导图
antigen
relative concept
immune response
antigen classification
mind map
