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注意偏向训练对康复期男性酒依赖患者注意偏向、心理渴求及复饮率的影响 被引量:2

Effects of attentional bias training on attention bias,psychological craving and relapse rate in male patients with alcohol dependence
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摘要 目的探讨注意偏向训练对康复期酒依赖患者注意偏向、心理渴求及复饮率的影响。方法采用随机对照试验,选取90名酒依赖患者,随机分为干预组和对照组,将酒精线索图片与中性图片按1∶1比例导入E-Prime软件,采用点探测范式分别对两组患者进行8次有注意偏向训练及无注意偏向训练,每次训练后软件自动记录对线索图与中性图的反应时及正确率,并在干预前(T0)、干预4次后(T4)和干预8次后(T8)采用视觉模拟量表测评酒精心理渴求评分及干预结束后1个月随访复饮情况。使用SPSS 24.0进行统计分析,采用重复测量方差分析、χ^(2)检验、t检验对两组患者的反应时、正确率、心理渴求进行组别及组内比较。结果重复测量方差分析显示,两组患者在线索图反应时、线索图正确率、心理渴求得分中均存在组别和时间的交互作用(F=5.218,6.939,147.14,均P<0.01),简单效应分析显示,干预组与对照组线索图反应时、线索图正确率、心理渴求得分在T0差异无统计学意义(均P>0.05),在T4、T8时均差异有统计学意义(均P<0.05),中性图反应时仅在T8差异有统计学意义(P<0.05);组内两两比较显示,干预组在线索图反应时呈下降趋势,T4、T8均小于T0(均P<0.001),对照组差异无统计学意义(均P>0.05);干预组在线索图正确率呈上升趋势,T4、T8均高于T0,差异有统计学意义(均P<0.001),对照组差异无统计学意义;干预组及对照组在心理渴求得分上均呈下降趋势,T4、T8均小于T0,差异有统计学意义(P<0.001),但对照组T4与T8之间维持不变(P>0.05)。干预结束后1个月时,干预组与对照组复饮率的差异处于边缘显著(11.10%,26.70%,P=0.059),干预组累计戒酒天数长于对照组[(28.33±4.99)d,(26.47±6.66)d,P=0.010]。结论注意偏向训练可改善康复期酒依赖患者心理渴求及注意偏向,干预后1个月时的复饮率有一定降低。 Objective To explore the effect of attentional bias training on the attentional bias,psychological craving and relapse rate of alcohol dependent patients during rehabilitation.Methods A randomized controlled trial was used to select 90 alcohol-dependent patients and randomly divide them into an intervention group and a control group.The alcohol cue pictures and neutral pictures were imported into E-Prime software at a ratio of 1∶1.The patients in the two groups were trained for eight times with attentional bias and without attentional bias by point delection paradigm.After each training,the software automatically records the response time and correct rate of the cue pictures and neutral pictures,and before intervention(T0),after 4 interventions(T4),and after 8 interventions(T8),the alcohol craving score was assessed by visual analogue scale and the relapse situation was followed up 1 month after the intervention.SPSS 24.0 software was used for statistical analysis.Repeat measure ANOVA,χ^(2)test and t-test were used to compare the response time,accuracy and psychological craving of the two groups.Results Repeated measurement analysis of variance showed that there were interaction between group and time in cue-map response time,line chart accuracy and psychological craving score of the two groups(F=5.218,6.939,147.14,all P<0.01).Simple effect analysis showed that there was no significant difference in cue pictures response time,cue pictures accuracy and psychological craving score between the intervention group and the control group at T0(all P>0.05),but there was significant difference at T4 and T8(all P<0.05),and there was significant difference in neutral pictures reaction only at T8(P<0.05).The comparison between two groups showed that the intervention group showed a downward trend in cue pictures response,T4 and T8 were lower than T0,with statistical difference(both P<0.001),while there was no difference in the control group.In the intervention group,the correct rate of cue pictures increased,T4 and T8 were
作者 高静 蔡壮 王志稳 杨可冰 牛雅娟 赵朝霞 张黎 Gao Jing;Cai Zhuang;Wang Zhiwen;Yang Kebing;Niu Yajuan;Zhao Zhaoxia;Zhang Li(Clinical Second Department,Beijing Huilongguan Hospital,Beijing 100096,China;School of Nursing,Peking University,Beijing 100191,China)
出处 《中华行为医学与脑科学杂志》 CAS CSCD 北大核心 2022年第2期128-135,共8页 Chinese Journal of Behavioral Medicine and Brain Science
基金 北京市医院管理中心"青苗"计划专项经费资助(QML20182002,QML20202002)。
关键词 注意偏向训练 酒依赖 心理渴求 注意偏向 复饮率 Attentional bias training Alcohol-dependent Psychological craving Attentional bias Relapse rate
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