摘要
目的总结分析兰州市部分新型冠状病毒肺炎患者的临床表现及影像学特征。方法回顾性分析2020年1月23日至2020年2月23日兰州大学第一医院新型冠状病毒肺炎隔离病房收治的8例确诊为新型冠状病毒肺炎患者的流行病学史、临床特点和影像学资料。结果8例患者中男女比例5∶3,年龄24~57岁。潜伏期在1~10 d,7例为境内输入性病例(87.5%),1例为2代感染病例(12.5%)。临床表现为咳嗽6例(75%),发热4例(50%),咳痰3例(37.5%),乏力2例(25%)。血常规检查均有异常表现,白细胞减少4例(50%),淋巴细胞减少7例(87.5%);LDH升高5例(62.5%),CK升高1例(12.5%),CK-MB升高1例(12.5%);CRP升高4例(50%),PCT升高2例(25%);D-二聚体升高1例(12.5%)。胸部影像学检查中2例行DR胸部正位片检查,1例无异常,1例为双肺纹理增重;6例行HRCT检查,4例(50%)有双肺多发磨玻璃样渗出影,2例(25%)有右肺多发磨玻璃渗出影,均无胸腔积液。6例患者经治疗痊愈出院,1例患者仍在院治疗中。结论8位COVID-19患者以输入性病例为主,年龄较轻,基础疾病少,主要表现为咳嗽、发热、咳痰等,所有患者均有血常规异常,半数CRP升高,少数患者出现肌酶及D-二聚体异常;多数患者影像学表现为靠近外周胸膜的、多发的磨玻璃影。
Objective To investigate and summarize the clinical and imaging features of a few patients with coronavirus disease 2019(COVID-19)in Lanzhou City.Methods We carried out a retrospective analysis of the epidemiological data,laboratory results and clinical imaging features of eight hospitalized patients with confirmed COVID-19 in The First Hospital of Lanzhou University from January 23 to February 23,2020.Results The sex ratio(men to women)of the 8 patients was 5∶3 while their age ranged from 24 to 57 years old.The incubation period was 1-10 days.Of the 8 patients,7(87.5%)had COVID-19 brought in from other places in China and 1(12.5%)was a secondary infection case.The main clinical manifestations included cough in 6 cases(75%),fever in 4 cases(50%),expectoration in 3 cases(37.5%),and fatigue in 2 cases(25%).All the 8 cases indicated abnormal manifestations in blood routine examinations,4 cases(50%)decreased in WBC,7 cases(87.5%)decreased in Lym count,5 cases(62.5%)increased in LDH,1 case(12.5%)increased in CK,1 case(12.5%)increased in CK-MB,4 cases(50%)increased in CRP,2 cases(25%)increased in PCT,and 1 case(12.5%)increased in D-dimer.Of the 2 patients examined by chest digital radiography(DR),one DR finding was not typical and the other one suggestedincreased bilateral lung markings.Six patients were examined by HRCT,of whom four(50%)showed multiple ground glass opacities on both lobes and two(25%)showed multiple ground glass opacities only on the right lobe;none of the 6 imaging findings suggested pleural effusion.Six patients were discharged from hospital after being cured and 1 patient still underwent treatment.Conclusion Most of these 8 patients had COVID-19 imported from outside the city,and the patients were relatively young with few underlying diseases.Their major symptoms were fever,cough,and expectoration.All of them exhibited abnormal findings in blood routine examinations;half of them suggested increased CRP while a few ones showed abnormal CK and Ddimer values.The imaging manifestations of most patien
作者
冯涛
岳红梅
濮家源
胡建明
汪小亚
鲁文强
李龙
刘维英
白雪
FENG Tao;YUE Hongmei;PU Jiayuan;HU Jianming;WANG Xiaoya;LU Wenqiang;LI Long;LIU Weiying;BAI Xue(Department of Respiratory and Critical Care Medicine, The First Hospital of Lanzhou University, Lanzhou 730000;The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China)
出处
《西安交通大学学报（医学版）》
CAS
CSCD
北大核心
2021年第1期113-117,共5页
Journal of Xi’an Jiaotong University（Medical Sciences）
基金
甘肃省应对新型冠状病毒感染的肺炎疫情科研攻关特别专项(2020)。
关键词
新型冠状病毒肺炎
流行病学
临床表现
影像学表现
coronavirus disease 2019(COVID-19)
epidemiology
clinical manifestation
imaging feature
