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胸腔镜肺叶切除术与肺段切除术治疗早期肺癌的效果及不良反应分析 被引量:6

Effect and Adverse Reactions of Thoracoscopic Lobectomy and Segmentectomy in the Treatment of Early Lung Cancer
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摘要 目的:分析早期肺癌患者采用胸腔镜肺叶切除术及肺段切除术治疗的效果及不良反应。方法:本次研究对象为2017年6月-2019年6月笔者所在医院收治的204例早期肺癌患者,根据手术方案的不同将其分为对照组和研究组,各102例。对照组行胸腔镜肺叶切除术,研究组行胸腔镜肺段切除术。比较两组手术效果。结果:研究组术后引流量(315.3±65.2)ml,术中出血量(66.3±16.9)ml、抗生素使用时间(2.8±0.6)d,住院时间(7.1±1.2)d,均优于对照组的(367.0±81.3)ml、(75.6±11.5)ml、(3.9±1.2)d、(9.5±1.5)d,差异有统计学意义(P<0.05)。两组术后肺功能指标均较术前降低,但研究组术后肺功能指标降低程度小于对照组,差异有统计学意义(P<0.05)。研究组不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。两组1年复发率及生存率比较差异无统计学意义(P>0.05)。结论:胸腔镜肺段切除术、胸腔镜肺叶切除术都是临床治疗早期肺癌的有效手段,胸腔镜肺段切除术的切除范围小,有效保留健康肺组织,对肺功能的影响更小,可降低术后不良反应发生率。 Objective:To analyze the effect and adverse reactions of thoracoscopic lobectomy and segmentectomy in the treatment of early lung cancer.Method:The subjects of this study were 204 patients with early lung cancer admitted in our hospital from June 2017 to June 2019.They were divided into the control group and the study group according to different surgical procedures,with 102 cases in each group.The control group underwent thoracoscopic lobectomy,while the study group underwent thoracoscopic segmentectomy.The operation effect of the two groups was compared.Result:The postoperative drainage volume(315.3±65.2)ml,intraoperative blood loss(66.3±16.9)ml,antibiotic use time(2.8±0.6)d and length of hospital stay(7.1±1.2)d in the study group which were all better than(367.0±81.3)ml,(75.6±11.5)ml,(3.9±1.2)d,(9.5±1.5)d in the control group,the differences were statistically significant(P<0.05).Postoperative lung function indexes in both groups were reduced compared with those before surgery,but the reduced degree of postoperative lung function indexes in the study group was lower than that in the control group,the differences were statistically significant(P<0.05).The incidence of adverse reactions in the study group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).There were no significant difference in one-year recurrence rate and survival rate between the two groups(P>0.05).Conclusion:Thoracoscopic segmentectomy and thoracoscopic lobectomy are both effective methods for the treatment of early lung cancer.The scope of thoracoscopic segmentectomy is small,effectively retains healthy lung tissue,has less impact on lung function,and can reduce the incidence of postoperative adverse reactions.
作者 潘闪 林铿强 代祖建 陈树兴 PAN Shan;LIN Kengqiang;DAI Zujian;CHEN Shuxing(Fuzhou Pulmonary Hospital,Fuzhou 350000,China;不详)
机构地区 福州肺科医院
出处 《中外医学研究》 2020年第29期27-29,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 早期肺癌 不良反应 肺叶切除术 胸腔镜 肺段切除术 Early lung cancer Adverse reactions Lobectomy Thoracoscopic Segmentectomy
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