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术前口服不同浓度含糖液对围手术期患者应激反应的影响 被引量:7

Study on effect of different concentrations of preoperative sugary drinks on stress response of patients during perioperative period
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摘要 目的探讨术前口服不同浓度含糖液对围手术期患者不同时段血糖、血清C反应蛋白、白蛋白及术后消化道症状的影响。方法将全麻下行择期手术的190例脊柱外科住院患者分为三组,于术日晨分别口服温开水(温开水组,58例)、5%葡萄糖溶液(5%葡萄糖组,67例)、12.5%葡萄糖溶液(12.5%葡萄糖组,65例)各350mL,0.5h内饮完。比较三组围手术期不同时间段血糖、血清C反应蛋白、白蛋白的变化趋势以及对术后患者消化道症状的影响。结果三组术前1h、术中、术后6h血糖值比较,差异有统计学意义(均P<0.01)。三组术后C反应蛋白、白蛋白值比较,差异无统计学意义(均P>0.05);三组不同时段C反应蛋白、白蛋白值组内比较,差异有统计学意义(均P<0.01)。三组术后腹胀发生率比较,差异有统计学意义(P<0.05)。结论术前口服含糖液可适度缓解患者围手术期应激性反应,5%葡萄糖溶液可减轻患者术后腹胀,临床术前可选择饮用。 Objective To explore the effects of different concentrations of sugar-containing drinks consumed preoperatively on serum glucose,serum C-reactive protein(CRP),and albumin levels,and postoperative gastrointestinal symptoms in patients at different time points of the perioperative period.Methods A total of 190 patients scheduled for elective spinal surgery under general anesthesia were divided into 3 groups based on the drinks(the warm boiled water group,the 5%glucose solution group,12.5%glucose solution group)they consumed in the morning of the operation day.All the patients were asked to finish the drinks(350 mL)within 0.5 h.The changes in fasting serum glucose,CRP and albumin levels and their effects on postoperative gastrointestinal symptoms were compared among the 3 groups at different time points.Results There were significant differences in serum glucose levels among the 3 groups 1 hour before surgery,during the surgery,and 6 hours after surgery(P<0.01 for all).There were no significant differences in CRP and albumin levels among the 3 groups postoperatively(P>0.05 for all),while there were significant differences in CRP and albumin levels within each group at all the time points(P<0.01 for all).Incidence rate of postoperative abdominal distension had significant differences among the 3 groups(P<0.05).Conclusion Oral sugary drinks before surgery can lessen perioperative stress levels.Among others,5%glucose solution can reduce abdominal distension after surgery,and can be used as a pre-operative drink.
作者 张振美 郭晓宇 史冬立 齐加新 Zhang Zhenmei;Guo Xiaoyu;Shi Dongli;Qi Jiaxin(Department of Nursing,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,China)
出处 《护理学杂志》 CSCD 北大核心 2020年第16期38-41,共4页 Journal of Nursing Science
关键词 脊柱手术 禁食 禁饮 葡萄糖溶液 应激反应 血糖 C反应蛋白 白蛋白 spine surgery fasting ban on fluid drinking glucose solution stress response serum glucose C-reactive protein albumin
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