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注射用兰索拉唑治疗十二指肠溃疡出血的临床效果研究 被引量:4

Clinical Efficacy of Lansoprazole for Injection in the Treatment of Duodenal Ulcer Bleeding
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摘要 目的:探讨注射用兰索拉唑治疗十二指肠溃疡出血的临床疗效。方法:将65例十二指肠溃疡出血患者分为对照组和观察组。对照组32例患者给予奥美拉唑钠治疗,观察组33例患者给予注射用兰索拉唑治疗。观察两组患者临床疗效、不良反应、止血时间及腹痛消失时间。结果:观察组临床有效率96.97%,明显高于对照组的75.00%,差异有统计学意义(P<0.05);观察组不良反应发生率为6.06%,显著低于对照组的12.50%(P<0.05)。观察组止血时间(28.21±8.52)h,腹痛消失时间(2.03±0.58)d,较对照组更短,差异有统计学意义(P<0.05)。结论:采取注射用兰索拉唑治疗十二指肠溃疡出血的临床疗效确切,不良反应少,能有效缩短患者止血时间及腹痛消失时间,在临床治疗中具有重要价值。 Objective:To investigate the clinical efficacy of Lansoprazole for Injection in the treatment of duodenal ulcer bleeding.Method:65 cases of patients with duodenal ulcer bleeding were divided into control group and observation group.The control group 32 cases were treated with Omeprazole Sodium and the observation group 33 cases were treated with Lansoprazole for Injection.The clinical efficacy and adverse reactions of the two groups were observed. Result:The clinical effective rate of the observation group was 97.22%,significantly higher than 73.33% of the control group,there was statistical significance(P<0.05).The incidence of adverse reactions in the observation group was 5.56%,significantly lower than 13.33% of the control group(P<0.05). The hemostasis time(28.21±8.52)h and the disappearance time of abdominal pain(2.03±0.58)d in the observation group were shorter than those in the control group(P<0.05).Conclusion:Lansoprazole for injection is effective in the treatment of duodenal ulcer hemorrhage with few adverse reactions,which is of great value in clinical treatment.
作者 吴惠君 颜晓婷 /WU Huijun;YAN Xiaoting(The Second People’s Hospital of Shanwei,Shanwei,516600,China)
出处 《中外医学研究》 2019年第18期58-59,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 注射用兰索拉唑 十二指肠溃疡出血 临床疗效 不良反应 Lansoprazole for injection Duodenal ulcer bleeding Clinical efficacy Adverse reactions
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