摘要
挥发油是中药中的重要活性成分之一。近年来中药挥发油抗肿瘤的研究备受关注,如抗肿瘤活性部位的筛选,抗肿瘤物质基础及作用机制的发掘,中药挥发油类抗肿瘤制剂的开发都是当前研究的热点。笔者以《中成药标准汇编》的数据库为依据,筛选出了20种具有抗肿瘤作用的中药挥发油,并对这20种挥发油在中成药中的应用情况,药材中挥发油的含量及主要成分,有效提取部位,抗肿瘤的类型,专利的获批及上市产品等方面进行了全面的统计与分析,希望能为中药挥发油抗肿瘤的深入研究和中药挥发油类制剂的系统开发提供一定的理论依据及参考。
Volatile oils are one class of the most important active ingredients in traditional Chinese medicine （TCM）. In recent years, the research on the anti-tumor TCM volatile oils has received much attention. Screening of anti-tumor active site, exploration of the mechanism of action of anti-tumor and substance basis, and development of anti-tumor preparations of TCM volatile oils are the fo- cus of current research. Twenty kinds of TCM volatile oils which have antitumor effects were selected from the ＂The compilation of Chi- nese medicine standard＂ database. Comprehensive statistics and analysis were carried out for their application, content and major com- ponents in the herbal medicines, the effective extraction parts and types of target tumors, granted patents, and marketed products, ai- ming to provide a theoretical basis and reference for in-depth study of anti-tumor TCM volatile oils and development of relevant prepara- tion systems.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2017年第15期1376-1380,共5页
Chinese Pharmaceutical Journal
基金
国家自然科学基金资助项目(81560657,81360630)
江西省自然科学基金资助项目(20142BAB205083)
江西省教育厅科学技术研究项目资助(GJJ13609)
江西省卫生计生委中医药科技计划项目资助(2015A049)
江西中医药大学重点学科建设项目资助(2012jzzdxk028)
关键词
挥发油
抗肿瘤
专利
应用
现状分析
volatile oil
anti-tumor
patent
application
current situation analysis
