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双波长激光腹腔镜下不阻断肾动脉保留肾单位手术的疗效 被引量:6

The efficiency of using dual laser system zero in off clamp nephron-sparing surgery
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摘要 目的探讨应用双波长激光进行不阻断肾动脉(零缺血)保留肾单位手术(nephron-sparing surgery,NSS)的效果。 方法2016年1月至2017年4月我院收治的24例肾肿瘤患者。男16例,女8例。年龄32~62岁,平均49岁。左肾肿瘤13例,右肾肿瘤11例。肿瘤最大径0.8~3.2 cm,平均1.9 cm。R.E.N.A.L评分3~6分,平均3.8分。中山评分3~5分,平均3.5分。零缺血指数(zero ischemia index,ZII)1~4,平均1.6。24例均全麻下行双波长激光腹腔镜下零缺血NSS。采用Evolve双频激光系统发射双波长激光(980 nm/1 470 nm),采用连续发射模式,发射功率60 W。按照常规后腹腔镜手术体位和步骤,分离肾动脉后以标识带标记但不阻断,沿肿瘤边缘正常肾组织以激光烧灼标记,然后以双波长激光沿肿瘤包膜切割。在肿瘤基底部将激光切割由垂直方向改为水平方向。创面内较大的血管断端以激光点状凝固,创面以倒刺线单层或者双层连续缝合。 结果本组24例手术中,22例顺利完成腹腔镜下零缺血NSS,2例因术中创面出血而阻断肾动脉。手术时间50~100 min,平均(74.2±16.7)min。术中出血量10~200 ml,平均(52.9±55.6)ml。术后伤口引流量20~150 ml,平均(65.4±34.4)ml。术后住院时间4~7 d,平均(5.2±0.9)d。术后未发生严重外科并发症。术前血肌酐48~112 μmol/L,平均(76.2±21.5)μmol/L;术后为54~122 μmol/L,平均(81.5±19.0)μmol/L,差异无统计学意义(P〉0.05)。病理诊断:肾透明细胞癌20例,肾嫌色细胞癌3例,乳头状肾细胞癌1例。24例随访1~12个月,平均(7.2±3.2)个月,均未见复发和转移。 结论双波长激光提供了一种进行零缺血NSS的有效选择,该技术可以在肾功能保护、术中出血及肿瘤切除三者之间达到一个相对的平衡。 ObjectiveTo evaluate the efficacy of using dual laser system in off clamp nephron-sparing surgery. MethodsWe used dual laser system in the patients who underwent off-clamp NSS between Jan 2016 and Apr 2016 in our institution. There were 16 males and 8 females with average age of 49 years. Mean tumor size was 1.9 cm (range 0.8-3.2 cm). The mean R. E.N.A.L. score was 3.8(range 3-6). The mean Zhongshan score was 3.5(range 3-5). The mean ZII(zero ischemia index)was 1.6(range 1-4). The Evolve Dual (980 nm/1 470 nm) laser system set at 60 W in continuous mode was used. ResultsOff-clamp NSS was successfully performed in 22 patients except for renal artery occlusion in 2 case. Mean operative time was 74 min(range 50-100 min); The average estimated blood loss was 52.9 ml(range 10-200 ml); Mean postoperative drainage was 65.4 ml(range 20-150ml); Mean postoperative hospital stay was 5.2 days (range: 4-7days). No severe post-operative complication was found. The mean pre- and postoperative serum creatinine levels were 76.2 μmol/L(range: 48-112μmol/L) and 81.5μmol/L(range: 54-122 μmol/L) with no significant difference(P〉0.05). The postoperative pathology indicated that 20 cases of clear cell carcinomas, 3 cases of chromophobe renal cell carcinomas, one case of papillary carcinoma. ConclusionsDual laser system can be used in off clamp nephron-sparing surgery safely and effectively.
出处 《中华泌尿外科杂志》 CAS CSCD 北大核心 2017年第7期511-514,共4页 Chinese Journal of Urology
关键词 保留肾单位手术 零缺血 肾肿瘤 双波长激光 Nephron sparing surgery Off-clamp Renal neoplasm Dual laser system
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