摘要
目的:探讨栀草风湿镇痛膏对急性软组织损伤大鼠PGE2的影响。方法:取SD大鼠,分成正常组、模型组、栀草风湿镇痛膏低剂量组、中剂量组、高剂量组及扶他林组,对比各组大鼠损伤组织PGE2含量变化。结果:与模型对照组比较,栀草风湿镇痛膏低、中、高剂量组和扶他林对照组均可降低损伤局部组织的PGE2的含量,治疗组与对照组之间有显著性差异(P<0.05)。结论:栀草风湿镇痛膏能抑制损伤局部的PGE2的含量,减少损伤局部炎性反应。
Objective： To investigate Zhi Cao Rheumatic E2 （PGE2） in rats acute injured tissue. Methods： SD rats and Analgesic Piaster on the contents of prostaglandin were divided into six groups, blank control group, model group,low dose group of Zhi Cao Rheumatic and Analgesic Piaster, medium dose group of Zhi Cao Rheumatic and Analgesic Piaster, high dose group of Zhi Cao Rheumatic and Analgesic Piaster and voltaren group , then the contents of IL - 1 βand PGE2 in the soft tissue homogenate were detected. Results： Compared with the model group, Zhi Cao Rheumatic and Analgesic Plaster low, medium and high dose groups and voharen group could decrease prostaglandin E2 （PGE2） in the tissue, there was significant differences between the treatment groups and control groups （ P 〈 0.05 ）. Conclusion ： Zhi Cao Rheumatic and Analgesic Plaster could inhibit the advancing level of PGE2 in injured soft tissue and aseptic inflammation on the injury tissue.
出处
《中国民族医药杂志》
2014年第5期39-41,共3页
Journal of Medicine and Pharmacy of Chinese Minorities
关键词
栀草风湿镇痛膏
急性软组织损伤
PGE2
Zhi Cao Rheumatic and Analgesic Piaster
acute soft tissue injury
PGE2
