摘要
目的 探讨以转移灶症状为首发症状就诊的卵巢上皮性癌 (EOC)的临床特点、治疗和预后。方法 自 1986年 1月～ 1997年 12月我院收治 2 5例盆腔病灶隐匿、最初表现均为远处转移灶症状的EOC患者 ,回顾性分析其临床资料。结果 首发症状为锁骨上和腹股沟淋巴结转移者最多见 ,分别为 6例和 5例 ;2个以上部位转移者 6例。 16例 ( 64% )术后盆腹腔残留灶直径≤ 1cm。 2 0例Ⅳ期患者的中位生存时间为 2 4个月 ;仅有锁骨上淋巴结或胸膜转移者中位生存时间为 3 0个月 ,明显高于其他部位转移患者的 19个月 (P =0 0 2 64)。结论 以转移灶症状为首发症状就诊的EOC预后较好 ,特别是仅有锁骨上淋巴结或胸膜转移者 。
Objective To study the characteristics, therapies and prognosis of the patients with epithelial ovarian cancer (EOC) that are initially categorized as extra abdominal adenocarcinoma of unknown primary Methods Twenty five patients with EOC, who were treated in the Cancer Hospital of Fudan University from Jan 1986 to Dec 1997, and manifesting as extra peritoneal or liver parenchyma metastases at the time of presentation, without detectable ovarian tumors, were retrospectively studied Results Supraclavicular and inguinal lymph node metastases were common in this group of patients, with 6 and 5 cases respectively, and 6 patients with more than two sites metastases simultaneously 16 patients (64%) were optimally surgical debulked 20 patients with stage Ⅳ EOC initially presenting as extra abdominal metastases experienced a better prognosis, with an estimated median survival of 24 months. Of whom the median survival was 30 months in patients presenting with pleural effusion or supraclavicular lymph node metastases Vs 19 months in those with other sites spread ( P =0 026 4) Conclusions The prognosis of such cases, particularly for those with supraclavicular lymphadenopathy or malignant pleural effusion, is a lot better than other stage Ⅳ EOC patients, probably because of most of the patients initially presenting with distant metastases being generally in a good condition competent for aggressive surgery or multi cycle chemotherapy
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
2001年第7期414-416,共3页
Chinese Journal of Obstetrics and Gynecology
关键词
卵巢肿瘤
妇科外科手术
肿瘤转移
预后
EOC
Ovarian neoplasms
Gynecologic surgical procedures
Neoplasm metastasis
Prognosis
