摘要
目的:了解妊娠期间红细胞各项参数、锌原卟啉、血清铁在不同孕期的变化规律,为孕期贫血的诊断提供依据。方法:采用全血细胞分析仪、国产ZPP-3800型血液锌原卟啉测定仪、全自动生化分析仪测定孕妇红细胞各参数、锌原卟啉及血清铁水平。结果:随孕周的增加,红细胞、血红蛋白、红细胞比积、平均红细胞体积、平均红细胞血红蛋白含量下降(P<0.01),红细胞分布宽度、锌原卟啉增高(P<0.01)。平均红细胞体积、平均红细胞血红蛋白含量以产后组为最低(P<0.01),红细胞分布宽度以产后组为最大(P<0.05)。孕晚期血清铁明显低于孕早期和孕中期(P<0.01)。结论:孕晚期血清铁下降明显,红细胞有向小细胞低色素发展的趋势,因此,在怀孕的中、晚期,应及时补充铁剂,防止缺铁性贫血的发生。
Objective： To understand the change regularities of red blood cell parameters, zinc protoporphyrin and serum iron during different periods of pregnancy, and provide a basis for diagnosis of anemia during pregnancy. Methods： Hematology analyzer, domestic ZPP - 3800 blood zinc protoporphyrin hematofluorometer and fully automatic biochemical analyzer were used to detect the levels of red blood cell parameters, zinc protoporphyrin and serum iron. Results： With increase of gestational week, red blood cell count, hemoglobin level, hematoerit, mean corpuscular volume and mean corpuscular hemoglobin content decreased （P 〈 0. 01 ）, red blood cell distribution width and zinc protoporphyrin level increased （P 〈 0. 01 ） . Mean corpuscular volume and mean corpuscular hemoglobin content in postpartum group were the lowest （ P 〈 0. 01 ）, while red blood cell distribution width in postpartum was the highest （P 〈 0. 05） . Serum iron level during the third trimester of pregnancy was statistically significantly lower than those during the first and the third trimesters of pregnancy （P 〈 0. 01 ） . Conclusion ： Serum iron level during the third trimester of pregnancy decreases significantly, there is a trend of turning to smaller and low hemoglobin in red blood cells ; thus, timely iron supplement is necessary to prevent the occurrence of iron - deficiency anemia.
出处
《中国妇幼保健》
CAS
北大核心
2014年第17期2703-2705,共3页
Maternal and Child Health Care of China
关键词
孕产妇
红细胞
锌原卟啉
血清铁
Pregnant woman
Red blood cell
Zinc protoporphyrin
Serum iron
