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尿苷二磷酸葡萄糖醛酸转移酶1A7基因多态性与抗结核药致肝损伤易感性的关系 被引量:8

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摘要 目前,结核病仍是威胁人类健康的重要传染性疾病之一,结核病控制的策略主要是药物的化学疗法。抗结核药物引起的肝毒性已位居药源性肝损伤的第1位。尿苷葡萄糖醛酸转移酶(UGT)是一种重要的Ⅱ相反应代谢酶,对外源性化合物具有解毒作用。
出处 《中华传染病杂志》 CAS CSCD 北大核心 2012年第3期174-178,共5页 Chinese Journal of Infectious Diseases
基金 国家自然科学基金资助项目(81041096) 唐山市重点实验室资助项目(08150201A-1-8 )
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