摘要
目的探讨血清孕酮联合β-人绒毛膜促性腺激素(β-HCG)在鉴别诊断正常妊娠和各种异常妊娠中的临床意义。方法采用回顾性队列分析,对158例各类妊娠病例1周内孕酮和β-HCG的变化进行动态分析比较。结果妊娠中血清孕酮和β-HCG并无正相关关系。在妊娠第4、5、6周时,血清孕酮若分别低于5、10、20ng/mL则提示妊娠异常,而血清β-HCG在妊娠前8周若平均每3～4天增长低于50%也提示妊娠异常。结论单次血清孕酮和β-HCG联合检测以及β-HCG的动态监测可辅助鉴别各类妊娠,是临床早期诊断各种异常妊娠的重要指标。
Objective To explore the clinical value of both serum progesterone and β-HCG in differentiating normal intrauterine pregnancy（IUP）from abnormal pregnancy.Methods The serum progesterone and β-HCG of 158 patients including all kinds of pregnancies within one week were analyzed by retrospective study.Results There was not a necessarily positive correlation between β-HCG levels and progesterone when pregnancy.The progesterone threshold value for abnormal pregnancy at 4 weeks was 5ng/mL,at 5 weeks 10 ng/mL and at 6 weeks 20 ng/mL,while the rise of β-HCG in average 3-4 d before 8 weeks duration was less than 50%,it was also suspected abnormal pregnancy.Conclusion The single detection of serum progesterone and its combined detection with β-HCG and dynamic monitoring of β-HCG could be helpful as significant indexes to early differentiate all kinds of prenancies for clinic.
出处
《检验医学与临床》
CAS
2010年第20期2200-2202,共3页
Laboratory Medicine and Clinic
