摘要
近年研究表明,雌激素是神经系统中一种重要的信号分子,在促进神经生长发育、可塑性、神经递质的合成乃至神经元的存活、髓鞘和轴突再生过程中起着重要作用。特别是雌激素在中风、老年性痴呆、帕金森病等中枢神经系统退行性疾病以及脊髓、坐骨神经损伤、急性脑出血、脑缺血、神经外伤等方面备受关注。但是关于雌激素在神经干细胞移植术、视神经损伤疾病中作用的报道还很少。我们就雌激素对神经的保护作用做一综述。
The study of recent years showed that estrogen is an important signaling molecule in the nervous system. It plays an important role in the process of promoting nerve growth and development, plasticity, neurotransmitter synthesis and even the survival of neurons, myelin and axon regeneration. It causes for concern particularly that how estrogen plays in the stroke, senile dementia, Parkinson＇s disease and other degenerative diseases of central nervous system and spinal cord, sciatic nerve injury, acute cerebral hemorrhage, cerebral ischemia, neural trauma, etc. However, it is rarely reported about the role of estrogen in neural stem cells transplantation and optic nerve disease. This article made a brief summary on the effect of estrogen on the protective effects of nerve.
出处
《国际眼科杂志》
CAS
2010年第3期523-526,共4页
International Eye Science
关键词
雌激素
雌二醇
神经保护
estrogen
estradiol
neuroprotection
