摘要
对环磷酰胺(CY)建立免疫抑制的家兔模型。以不同途径(口服、直肠、肌注、盐水对照)给予猪脾转移因子(TF—p)后,观察白细胞总数的变化。结果表明:经肌肉注射、口服、直肠给药后第3天,各组白细胞总数迅速上升,而以直肠组白细胞总数上升最快,第5天出现反馈性增高,第8天后趋向正常。
An immune inhibited model of rabbits had been established with cyclophomidum (CY), which was taken up the porcine spleen—transfer factor (TF—p)in the different way (in oral,in rectal,injecting in muscle and with normal saline in control)later.Finally it was counted the changes of the WBC.The results showed that the WBC rising rapidly after three days using in o- ral,rectal and injecting.The WBC counts in the rectal usage-way were the highest among the three ways and in the fifth day the WBC counts were higher than normal and in the eighth day the WBC counts tended to normal.
出处
《潍坊医学院学报》
1993年第4期268-269,共2页
Acta Academiae Medicinae Weifang
关键词
转移因子
免疫抑制
环磷酰胺
transfer factor
immune inhibited
cyclophomidum
