摘要
目的分析儿童包皮粘连手法分离中使用奥布卡因凝胶的镇痛效果及安全性。方法选取86例实施包皮粘连手法分离患儿,按镇痛药物不同划分为研究组(43例)和对照组(43例)。对照组患儿不采用任何镇痛药物,研究组患儿使用奥布卡因凝胶镇痛。比较两组患儿镇痛前后的血流动力学指标,术后0.5、2 h的镇痛情况,手术总用时和疼痛恢复时间,术后并发症发生情况。结果镇痛前两组患儿的血流动力学指标无显著差异(P>0.05);镇痛后研究组患儿的心率(95.31±5.18)次/min比对照组的(100.46±6.29)次/min低,呼吸频率(20.15±1.03)次/min、血氧饱和度(98.01±0.32)%比对照组的(18.36±1.25)次/min、(96.05±0.48)%高,差异有统计学意义(P<0.05)。术后2 h,两组患儿的镇痛评分均比本组术后0.5 h低,且术后0.5、2 h研究组患儿镇痛评分(5.01±0.76)、(3.54±1.05)分均比对照组的(7.52±0.78)、(4.92±1.01)分低,差异有统计学意义(P<0.05)。研究组患儿手术总用时(26.46±4.21)min、疼痛恢复时间(73.43±10.41)min均比对照组的(31.54±5.16)、(122.57±15.32)min短,差异有统计学意义(P<0.05)。研究组患儿并发症发生率6.98%与对照组的23.26%相比更低,差异有统计学意义(P<0.05)。结论儿童包皮粘连手法分离中使用奥布卡因凝胶具有更好的镇痛效果,可有效改善患儿的血流动力学指标,使其疼痛程度有效降低,减少患儿手术时间,且患儿使用后不会有严重的并发症,具有较高的安全性。
Objective To analyze the analgesic effect and safety analysis of oxybuprocaine gel in manual separation of adherent prepuce in children.Methods A total of 86 children receiving manual separation of adherent prepuce were divided into a study group(43 cases)and a control group(43 cases)according to different analgesic drugs.Children in the control group did not use any analgesic drugs,and children in the study group used oxybuprocaine gel for analgesia.The hemodynamic indexes before and after analgesia,analgesia at 0.5 and 2 h postoperatively,total operation time and pain recovery time,and the occurrence of postoperative complications were compared between the two groups.Results Before analgesia,there were no significant differences in hemodynamic indexes between the two groups(P>0.05).After analgesia,the heart rate of(95.31±5.18)beats/min in the study group was lower than(100.46±6.29)beats/min in the control group;the respiratory rate and oxygen saturation were(20.15±1.03)beats/min and(98.01±0.32)%in the study group,which were higher than(18.36±1.25)beats/min and(96.05±0.48)%in the control group;the difference was statistically significant(P<0.05).At 2 h postoperatively,the analgesia score in both groups were lower than that at 0.5 h postoperatively in this group;at 0.5 and 2 h postoperatively,the analgesic scores were(5.01±0.76)and(3.54±1.05)points in the study group,which were lower than(7.52±0.78)and(4.92±1.01)points in the control group;the difference was statistically significant(P<0.05).The study group had total operation time of(26.46±4.21)min and pain recovery time of(73.43±10.41)min,which were shorter than(31.54±5.16)and(122.57±15.32)min in the control group,and the difference was statistically significant(P<0.05).The complication rate of 6.98%in the study group was lower than 23.26%in the control group,and the difference was statistically significant(P<0.05).Conclusion The use of oxybuprocaine gel in the manual separation of adherent prepuce in children has better analgesic effect,and can e
作者
汤鹏飞
TANG Peng-fei(Department of Pediatric Surgery,Weihai Maternal and Child Health Hospital,Weihai 264200,China)
出处
《中国现代药物应用》
2024年第20期99-102,共4页
Chinese Journal of Modern Drug Application
关键词
奥布卡因凝胶
包皮粘连
手法分离
镇痛效果
安全性
Oxybuprocaine gel
Adherent prepuce
Manual separation
Analgesic effect
Security
