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左氧氟沙星治疗慢性乙型肝炎合并肺结核的效果及安全性分析 被引量:1

Effect and Safety of Levofloxacin in Treatment of Chronic Hepatitis B Complicated with Pulmonary Tuberculosis
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摘要 目的观察左氧氟沙星用于慢性乙型肝炎合并肺结核患者的治疗效果及安全性。方法选取2015年12月至2017年12月收治的80例慢性乙型肝炎合并肺结核患者,按照治疗方案的不同分为两组,各40例,对照组予以化疗,研究组加用左氧氟沙星。对比两组治疗完成率、痰菌转阴率、病灶吸收率以及不良反应率。结果研究组的治疗完成率、痰菌转阴率、病灶吸收率均高于对照组,不良反应率低于对照组,差异有统计学意义(P<0.05)。结论在化疗的基础上加用左氧氟沙星可以提高对慢性乙型肝炎合并肺结核的治疗效果,同时不会发生严重不良反应。 Objective To investigate the therapeutic effect and safety of levofloxacin in patients with chronic hepatitis B complicated with pulmonary tuberculosis. Methods Eighty patients with chronic hepatitis B and tuberculosis who were admitted between December 2015 and December 2017 were divided into two groups according to their treatment options,40 cases each. The control group was treated with chemotherapy,the study group was treated with levofloxacin. The completion rate of treatment,sputum negative rate,the rate of lesion absorption and adverse reaction rate were compared between groups. Results The completion rate of treatment,the negative rate of sputum and the rate of lesion absorption were all higher in the study group than those in the control group. The adverse reaction rate was lower in the study group than in the control group(P<0.05). Conclusions The addition of levofloxacin on the basis of chemotherapy can improve the treatment effect of chronic hepatitis B complicated by pulmonary tuberculosis without serious adverse reactions,which is safe and effective.
作者 张蕴秀
出处 《大医生》 2018年第Z1期27-28,共2页 Doctor
关键词 左氧氟沙星 慢性乙型肝炎 肺结核 效果 安全性 levofloxacin chronic hepatitis B tuberculosis effect safety
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