摘要
目的:探讨三黄泻心汤联合奥美拉唑治疗对抗血小板聚集药物所致上消化道出血患者疗效及血流动力学的影响。方法:选取2013年7月至2015年9月我院收治上消化道出血患者中由抗血小板药物所致的上消化道出血180例。随机分为2组:A组90例,采用三黄泻心汤联合奥美拉唑治疗;B组90例,采用垂体后叶素治疗,观察记录2组患者止血时间,对比2组患者治疗疗效,治疗前后脾静脉和门静脉血流量。结果:治疗前2组患者脾静脉和门静脉差异未见统计学意义(P>0.05);治疗后,2组患者脾静脉和门静脉均有所下降,且A组患者下降的幅度大于B组,差异有统计学意义(P<0.05)。A组患者止血时间(15.37±5.43)h,短于B组止血时间(22.35±6.13)h,差异有统计学意义(P<0.05)。A组总有效率95.56%;B组总有效率71.11%,2组患者治疗总有效率,差异有统计学意义(P<0.05)。结论:三黄泻心汤与奥美拉唑联合治疗抗血小板药物所致上消化道出血疗效显著,能有效的改善患者血流动力学。
Objective：To study sanhuangxiexin decoction combined with omeprazole on curative effect and hemodynamics in patients with upper digestive tract hemorrhage induced by anti-platelet aggregation drugs.Methods：Totally 180 cases of upper digestive tract hemorrhage caused by anti-platelet drugs hospitalized from July 2013 to September 2015 were randomly divided into two groups：90 cases in group A,treated with sanhuangxiexin decoction combined with omeprazole;90 cases in group B,treated with pituitrin,observing hemostasis time and comparing curative effect between the two groups as well as blood flow rate of spleen vein and portal vein before and after the treatment.Results：Before treatment,there was no statistical difference in two groups of patients＆#39; spleen vein and portal vein （P〉0.05）;after treatment,all patients＇ spleen vein and portal vein decreased,group A more heavily,and the difference was statistically significant （P〈0.05）.Patients of group A had with less bleeding time （15.37±5.43） h than that of group B （22.35±6.13） h,and there was statistically significant difference （P〈0.05）.The total effective rate was 95.56% in group A,71.11% in group B,and the difference had statistical significance （P〈0.05）.Conclusion：Sanhuangxiexin decoction combined with omeprazole has clear curative effect in patients with upper digestive tract hemorrhage induced by anti-platelet aggregation drugs.and can effectively improve hemodynamics in patients.
出处
《世界中医药》
CAS
2017年第4期794-796,799,共4页
World Chinese Medicine
基金
武汉市卫生局科研项目(编号:ZC2012-12)
关键词
三黄泻心汤
上消化道出血
奥美拉唑
抗血小板药物
Sanhuangxiexin decoction
Hemorrhage of upper digestive tract
Omeprazole
Anti-platelet drugs
