摘要
目的探讨选择性心理干预护理模式对乳腺癌化疗患者免疫功能和焦虑抑郁不良情绪的评分。方法选取本院2014年2月～2015年6月收治的90例乳腺癌行化疗的患者作为研究对象，将2014年2～10月收治的45例患者作为对照组，而将2014年11月～2015年6月收治的45例患者作为观察组。其中对照组患者采用常规性化疗和健康教育护理模式，而观察组患者则在此基础上同时采用选择性心理干预护理模式。采用抑郁量表、焦虑量表和症状自评量表（SCL-90）对两组患者的心理行为进行评定，分析其不良情绪，同时采用放射免疫法对其外周血清中的白介素-2（IL-2）、白介素-4（IL-4）和肿瘤坏死因子（TNF-γ）的水平进行分析。结果经过相应的护理后，两组患者的焦虑抑郁等不良情绪评分均明显下降（P〈0．05），其中观察组患者的评分明显低于对照组（P〈0．05）；观察组患者外周血清中的IL-2和IL-4水平均明显升高（P〈0．05），而TNF-γ稍有增高，但不具有显著性差异性（P〉0．05）。结论选择性心理干预护理模式可明显改善乳腺癌化疗患者的焦虑抑郁等不良情绪，还可使其外周血中的细胞因子水平升高，增强其免疫功能，具有较好的应用效果。
Objective To explore the influence of selective psychological intervention nursing mode to immunologic function and anxiety and depression bad mood score of breast cancer patients with chemotherapy. Methods 90 cases of breast cancer patients with chemotherapy in our hospital from Feburary 2014 to June 2015 were selected as the study objects. 45 cases cured from February 2014 to October 2014 were divided into control group, and 45 cases cured from November 2014 to June 2015 were divided into observation group. Patiens in control group were treated with routine chemotherapy and health education nursing model, and patients in observation group were treated with selective psychological intervention nursing mode on the basis of control group. Self-ratingdepression scale （SDS）,Self-rating anxiety scale （SAS） and SCL- 90 were used to evaluate the psychological behavior of the two groups. The bad mood was analyzed. The radioimmunoassay was used to analyze the levels of interleukin-2 （IL-2）, interleuk-4 （IL- 4）, and tumor necrosis factor- γ （TNF- γ） in peripheral serum. Results After the corresponding nursing,anxiety, depression and other adverse emotional scores of the two grous were significantly decreased （P 〈 0.05）. The score of the observation group was significantly lower than that of the control group （P 〈 0.05）. The levels of IL-2 and IL-4 in peripheral serum of observation group were significantly increased （P 〈 0.05）. TNF- γwas slightly increased, but did not have significant differences （P 〉 0.05）. Conclusion The selective psychological intervention nursing mode can significantly improve the anxiety and depression of patients with breast cancer chemotherapy and other adverse emotional. And it can increase the cytokines levels in peripheral blood, and enhance its immune function. It has good application effects.
出处
《中国医药科学》
2016年第20期104-107,共4页
China Medicine And Pharmacy
关键词
选择性心理干预
乳腺癌
免疫功能
不良情绪
Selective psychological intervention
Breast cancer
Immune function
Bad mood
