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信宜地区围产儿出生缺陷危险因素的研究

Study on the Risk Factors of Perinatal Birth Defects in Xinyi Area
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摘要 目的研究信宜地区围产儿出生缺陷的危险因素及防范措施。方法选择信宜地区2013年4月至2015年4月期间住院分娩的孕妇1 168例,观察孕妇妊娠结局并统计围产儿出生缺陷情况。采用问卷调查形式对孕妇资料进行记录收集,并采用Logistic回归方程进行计算,观察影响围产儿出生缺陷的危险因素,并制定防范措施。结果 1 168例围产儿中169例(14.47%)有出生缺陷,男性出生缺陷围产儿96例(15.09%),女性出生缺陷围产儿73例(13.72%),出生缺陷围产儿性别对比无显著差异(P>0.05)。其中最常见类型为先天性心脏病,占28.99%,其次为血管瘤、外耳畸形、多指(趾)、脐疝、并指(趾)以及唇腭裂。孕妇年龄、文化程度、孕次、分娩方式及妊娠并发症均与出生缺陷有关(P<0.05),Logistic回归分析显示,年龄、文化程度、孕次、分娩方式及妊娠并发症均是围产儿出生缺陷的危险因素(P<0.05)。结论孕妇的年龄、文化程度、孕次、分娩方式及妊娠并发症均是围产儿出生缺陷的危险因素,孕妇在妊娠时需要针对上述问题采取针对性措施,进行指导和干预。 Objective To study the risk factors ofperinatal birth defects in Xinyi area and preventive measures. Methods 1 168 pregnant women who delivered in Xinyi region from April 2013 to April 2014 were selected. The pregnancy outcomes were observed and perinatal birth defects were counted, the data of pregnant women were collected and recorded by questionnaire survey form, and calculated by Logistic regression equation, the risk factors ofperinatal birth defects were observed and the preventive measures were made. Results Of 1 168 perinatal infants, 169 cases (14.47%) had birth defects, with 96 cases (15.09%) in male and 73 cases (13.72%) in female, the gender comparison in perinatal birth defects had no statistical difference (P 〉0.05). One of the most common type was congenital heart disease, accounted for 28.99%, followed by hemangioma, external ear malformation, polydactyly, umbilical hernia, syndactylia, and cleft lip and palate. The age, degree of education, time of pregnancy, delivery way, pregnancy complications of pregnant women were associated with birth defects (P 〈0.05). The Logistic regression analysis showed than the age, degree of education, time of pregnancy, delivery way, pregnancy complications of pregnant women were the risk factors of perinatal birth defects (P 〈0.05). Conclusions The age, degree of education, time of pregnancy, delivery way, pregnancy complications of pregnant women are the risk factors of perinatal birth defects. Pregnant women should take specific measures according to the above problems for guidance and intervention.
作者 罗冰 谢芳
出处 《临床医学工程》 2016年第6期829-830,共2页 Clinical Medicine & Engineering
关键词 出生缺陷 围产儿 危险因素 信宜 研究 防范措施 Birth defect Perinatal infant Risk factor Xinyi Research Preventive measure
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