摘要
目的分析探讨格列吡嗪、沙格列汀治疗2型糖尿病的临床疗效。方法在2014年1月—2015年8月期间来该院接受治疗的2型糖尿病患者中随机抽取78例,按照双盲法分成两组,对照组39例,应用格列吡嗪对患者进行治疗,观察组39例,应用沙格列汀对患者进行治疗,对比两组患者的临床治疗效果、治疗前后糖化血红蛋白水平以及不良反应发生情况。结果经治疗,两组患者临床疗效相近,无显著性差异(P>0.05);两组患者的糖化血红蛋白水平均有明显改善,治疗前后对比具有显著性差异(P<0.05),治疗后,两组患者的糖化血红蛋白水平相近,无显著性差异(P>0.05);观察组患者治疗后低血糖发生率明显低于对照组,具有显著性差异(P<0.05)。结论在2型糖尿病的临床治疗上,格列吡嗪和沙格列汀均疗效显著,但沙格列汀导致低血糖的发生率更低,安全性更高。
Pbjective To analyze glipizide, sand Glenn dean clinical curative effect for the treatment of type 2 diabetes.Methods From January 2014 to August 2014 to our hospital for treatment of patients with type 2 diabetes during a random sample of 78 cases, according to the double blind method is divided into two groups, control group 39 cases, the treatment of patients with application of glipizide group 39 cases, application of sand columns for the treatment of patients with statins, compared two groups of clinical treatment, before and after treatment in patients with a1 c levels and adverse reactions occur. Results After treatment, the clinical efficacy of two groups of patients, there was no significant difference（P〉0.05）;Two groups of patients with glycated hemoglobin levels were significantly improved, compared with significant difference before and after treatment（P〈0.05）, after treatment, two groups of glycosylated hemoglobin levels in patients with similar,there was no significant difference（P〉0.05）; After treatment in patients with hypoglycemia incidence of observation group was obviously lower than the control group, with significant difference（P〈0.05）. Conclusion In clinical treatment for type 2diabetes, glipizide and Glenn dean, curative effect is obvious, but Glenn dean sand cause a lower incidence of hypoglycemia, higher security.
出处
《糖尿病新世界》
2015年第24期41-43,共3页
Diabetes New World Magazine
关键词
格列吡嗪
沙格列汀
2型糖尿病
临床疗效
Glipizide
Sand Glenn dean
Type 2 diabetes
Clinical curative effect
