摘要
目的 探讨间苯三酚联合黄体酮治疗先兆流产的临床疗效。方法选择2011年9月—2013年7月间于该院就诊并治疗的先兆流产妊娠期妇女96例,采用随机数字表法分组,分别采用苯三酚联合黄体酮及单纯黄体酮肌注治疗,统计两组妊娠期妇女症状缓解及消失时间、血孕酮水平、保胎成功率及不良反应发生情况。结果联合治疗组患者的症状缓解时间及消失时间均较黄体酮组显著缩短(P<0.01);治疗后,两组妊娠期妇女的血孕酮水平均较治疗前显著升高(P<0.05),而联合治疗组较黄体酮组的升高程度更加明显(P<0.05);联合治疗组的保胎成功率显著升高(P<0.01);两组间不良反应发生率间差异无统计学意义(P>0.05)。结论采用间苯三酚联合黄体酮治疗先兆流产具有良好的疗效,提高了保胎成功率,且安全性好。
Objective To study the clinical curative effect of phloroglucinol combined with progesterone in the treatment of threatened abortion. Methods 96 pregnancy women with threatened abortion diagnosed and treated in our hospital from September 2011 to July 2013 were selected and randomly divided into two groups, treated by intramuscular injection of phloroglucinol combined with progesterone, and intramuscular injection of simple progesterone, respectively. The symptoms remission and disappearance time, blood progesterone levels, success rate of miscarriage and incidence of adverse reactions of the two groups were counted.Results The symptoms remission and disappearance time of the combined treatment group was much shorter than that of the progesterone group（P0.01）; after treatment, the blood progesterone levels of both groups increased significantly compared with those before treatment（P0.05）, but the blood progesterone level of the combined treatment group increased more obvious（P0.05）; the success rate of miscarriage of the combined treatment group was more higher（P0.01）; there was no statistically significant difference in the incidence of adverse reactions between the two groups（P0.05）. Conclusion Phloroglucinol combined with progesterone in the treatment of threatened abortion has good curative effect, which can improve the success rate of miscarriage with good safety.
出处
《中外医疗》
2014年第35期18-19,共2页
China & Foreign Medical Treatment
关键词
间苯三酚
黄体酮
先兆流产
不良反应
Phloroglucinol
Progesterone
Threatened abortion
Adverse reactions
