摘要
目的 :研究内分泌紊乱在牙周炎发病中的作用。方法 :SD雄性大鼠 6 4只 ,分对照组、单纯结扎组、单纯激素组及激素 +结扎组。肌注醋酸可的松混悬液致内分泌紊乱 ,15 d后用牙颈部丝线结扎法诱发牙周炎 ,观察近中牙槽骨高度和牙周组织的病理学改变。结果 :激素 +结扎组与其他各组相比 ,近中牙槽骨高度明显降低 (P<0 .0 5 ) ,并发现牙周炎的组织病理学改变。 结论 :在牙周炎的发病中 。
Objective: To investigate the effect of endocrine disturbance on occurrence of periodontitis. Methods: Sixty four SD male rats were divided randomly into four groups (control, simple ligation, simple hormone, hormone and ligation). Experimental periodontitis was initiated by ligation on day 15 of cortisone acetate injection. Mesial alveolar bone height and periodontal histologic changes were observed. Results: Compared with the other three groups, the height of mesial alveolar bone decreased obviously ( P <0.05) in the hormone and ligation group. And histologic changes of periodontitis were observed. Conclusion: Endocrine disturbance plays an important role in peirodontitis. [
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2000年第12期1166-1168,F003,共4页
Academic Journal of Second Military Medical University
