摘要
目的探讨抗肿瘤药物的不良反应情况及处理措施。方法回顾分析2005年3月至2010年8月收治的抗肿瘤药物不良反应情况,搜集并分析患者一般情况、用药情况及不良反应发生情况。结果抗肿瘤药物不良反应最常见类型为消化道反应(64.7%),其次为过敏反应(11.8%),以下依次发热(9.8%),血液系统反应(6.9%),肝脏毒性(3.9%),心脏毒性3例(2.9%)。102例不良反应中,评定为肯定9例,占全部不良反应病例8.8%;很可能67例,占全部不良反应病例65.7%;可能26例,占全部不良反应病例25.5%。男性略多于女性,60岁以上老年患者多见。结论抗肿瘤药物不良反应应引起广大医务工作者重视,尤其应关注60岁以上老龄患者。
Objective To explore the adverse reactions of antitumor drugs and measures for treatment.Methods The data of adverse reactions of antitumor drugs collected in March 2005 to August 2010 were retrospectively analyzed in order to realize the general situation of drug application and condition of adverse reactions in patients.Results The most common adverse reactions of antitumor drugs were gastrointestinal reactions（64.7%）,followed by allergic reactions（11.8%）,fever（9.8%）,reactions of blood system（6.9%）,liver toxicity（3.9%） and cardiac toxicity（2.9%） in 102 cases with adverse reactions.Among them,evaluation was sure in 9 cases,accounting for 8.8%,probable in 67 cases（65.7%） and possible in 26 cases（25.5%）.In these patients,males were slightly more than females.The adverse reactions of drugs were more possibly seen in patients with age of 60 years old or over.Conclusion Medical personnel should pay more attention to adverse reactions of antitumor drugs especially in patients with 60 years or older.
出处
《临床和实验医学杂志》
2012年第10期746-747,共2页
Journal of Clinical and Experimental Medicine
关键词
抗肿瘤药物
不良反应
防治
Antitumor drugs
Adverse reaction
Prevention and control
