摘要
胃肠运动失调、免疫抑制、肠黏膜屏障功能紊乱致肠道细菌过度繁殖和肠道细菌易位(BT),是重症急性胰腺炎(SAP)患者继发感染和脓毒血症的主要机制。充足的肠黏膜血氧供应和营养支持,可保护肠黏膜屏障的完整性,是预防BT的主要途径。本文就SAP继发感染和脓毒血症与BT的关系及其治疗策略作一综述。
Intestinal bacterial overgrowth and subsequent bacterial translocation （BT） due to motility disorders of digestive system, immunosuppression and failure of the intestinal mucosal barrier constitute the main pathway of secondary infection and sepsis in patients with severe acute pancreatitis （SAP）. Keeping the intestinal mucosal barrier intact by adequate oxygen supply and nutrient supplementation is the main issue in the prevention of BT. This article reviewed infection and consequent sepsis of SAP, its relationship with BT and treatment strategy.
出处
《胃肠病学》
2011年第4期250-252,共3页
Chinese Journal of Gastroenterology
关键词
细菌移位
胰腺炎
急性坏死性
感染
Bacterial Translocation
Pancreatitis, Acute Necrotizing
Infection
