摘要
①目的探讨人巨细胞病毒（ＨＣＭＶ）特异性转移因子（ＳＴＦ）对活动性巨细胞病毒感染孕妇的治疗作用。②方法以孕妇血清ＨＣＭＶ特异性ＩｇＭ阳性做为ＨＣＭＶ活动性感染的指标，应用普通转移因子（ＴＦ）、高效价免疫球蛋白（ＨＩＧ）及ＳＴＦ分别对５７例、１８例及４６例感染孕妇进行治疗，以血清ＨＣＭＶ－ＩｇＭ转阴作为有效的指标。③结果ＴＦ组的ＨＣＭＶ－ＩｇＭ转阴率为２８．１％（１６／５７）；ＨＩＧ组的转阴率为５５．５％（１０／１８）；ＳＴＦ组的转阴率为５６．５％（２６／４６）。ＳＴＦ的治疗作用优于ＴＦ（χ２＝９．７８０，Ｐ＜０．０１）；而ＳＴＦ与ＨＩＧ对感染孕妇的治疗作用无显著性差异（χ２＝０．０１，Ｐ＞０．０５）。④结论ＳＴＦ对活动性ＨＣＭＶ感染孕妇具有较好的治疗作用。
Objective To study the therapeutic effect of specific transfer factor on pregnant women with active human cytomegalovirus(HCMV) infection. Methods Specific IgM positive in the serum of pregnant woman was considered active infection of HCMV. Common transfer factor(TF), high titre immunoglobulin(HIG) and specific transfer factor(STF) were used to treat actively infected pregnant women respectively.The turning of specific IgM to negativity was an index of recovery. Results The rate of turning to negativity was 28.1%(16/57) in TF group,55.5%(10/18) in HIG group and 56.5%(26/46) in STF group respectively. The therapeutic effect of STF was superior to TF( χ 2=9.78, P <0.01) ; There was no difference between HIG and STF. Conclusion The STF has better therapeutic effect on pregnant woman with active HCMV infection.
出处
《青岛医学院学报》
1997年第3期237-238,共2页
Acta Academiae Medicinae Qingdao Universitatis
基金
山东省科委基金
