摘要
目的评价ABCD评分对短暂性脑缺血发作（TIA）后7d和90d脑梗死发生的急诊评估价值。方法以2006—01～2007—06住院的TIA患者为研究对象，收集其临床资料、磁共振弥散加权成像（DWI）和磁共振血管成像（MRA）的检查结果，按ABCD评分标准完成评分。随访TIA后7d和90d脑梗死的发生率，并分析ABCD评分与TIA后短期脑梗死发生的关系。结果TIA后90d共35例（30．7％）发生脑梗死，其中24例（21．1％）发生于7d内；ABCD评分与TIA后7d和90d脑梗死发生之间有直线相关关系，ABCD评分越高，脑梗死的发生率越高（P〈0．001）；多因素Logistic回归分析发现，ABCD评分（OR2．80.95％CI1．37～5．68，P=0．005）是TIA后7d脑梗死发生的独立危险因素，ABCD评分（OR2．64.95％CI1.39～4.93，P=0．003）和DWI异常（OR5．84.95％CI1.08～31.66，P=0．041）是TIA后90d脑梗死发生的独立危险因素。结论ABCD评分是急诊预测TIA短期预后的一种简单、有效的方法，结合DWI结果可以提高其对TIA后90d脑梗死的预测价值。
Objective To evaluate the ability of ABCD score in predicting cerebral infarction of transient isehemie attack （ TIA） patients at 7th and 90th day. Methods Clinical data, diffusion - weighted imaging （ DWI） and magnetic resonance angiography （MRA） findings were collected in a cohort of hospitalized TIA patients from January 2006 to June 2007. The ABCD score was applied to all the patients and used to stratify the 7 - day and 90 - day cerebral infarction risk. Results A total of 35 （ 30.7% ） patients had cerebral infarction within 90 days after symptoms onset, while 24 （21. 1% ）patients occurred within 7 days. Linear correlation existed between ABCD score and short - term risk of cerebral infarction in TIA patients（ P 〈0.001）. The higher the score was, the higher the incidence was. By multiple Logistic regression analysis, ABCD score （ odds ratio[ OR] ,2.80; 95% confidence interval [ CI], 1.37 - 5.68 ; P = 0. 005 ） was an independent predictor of 7 - day risk of cerebral infarction. At the same time, ABCD score （0R,2.64; 95% CI, 1.39 -4.93; P =0. 003） and DWI abnormality （ OR, 5.84; 95% CI, 1.08- 31.66; P = 0. 041 ） were independently associated with 90 -day risk of cerebral infarction. Conclusions The ABCD score is simple and effective to predict short - term risk of cerebral infarction in the patients with TIA. Combination with the information of DWI can improve the predictive accuracy of 90 - day risk of cerebral infarction after TIA.
出处
《中国急救医学》
CAS
CSCD
北大核心
2008年第3期193-196,共4页
Chinese Journal of Critical Care Medicine
基金
洛阳市科技发展计划项目(No0701015B)
关键词
脑缺血发作
短暂性
ABCD评分
脑梗死
预后
Transient ischemic attack（TlA）
ABCD score
Cerebral infarction
Prognosis
