摘要
目的：运用统计学方法处理６５例生长激素缺乏患者的鞍区ＭＲＩ改变的结果，得到垂体性和下丘脑性生长激素缺乏的相关统计函数式，提出诊断数据化处理的意义和可能性。材料与方法：６５例原发性生长激素缺乏患者，其中下丘脑性生长激素缺乏（ＨＧＨＤ）１５例，垂体性生长激素缺乏（ＰＧＨＤ）５０例。使用ＴＯＳＨＩＢＡ公司的０．３５Ｔ超导ＭＲＩ成像系统对患者进行３ｍｍ层厚的鞍区检查。得到每个患者ＭＲＩ征象６个方面参数６５组数据。随机分为统计组和检验组，用统计组的数据运用判别分析原理（多个数据的两类判别）求导它们的相关函数式，运用ｔ或χ２检验，判别参数与诊断相关意义。用检验组验证方程式的诊断符合率。结果：得到两类侏儒的判别函数式。垂体高径（Ｘ１），垂体后叶（Ｘ２），垂体柄（Ｘ３），鞍窝形态（Ｘ４）有高度统计学意义。判别函数式的诊断符合率为８８．９‰。结论：（１）两型侏儒具有明显的鞍区表现差异，ＭＲＩ检查是有效的诊断方法；（２）统计学结果具有明显的临床实用意义。
Objective: To establish and evaluate the correlative statistic discriminants of pituitary growth hormone deficiency (PGHD) and hypothalamic growth hormone deficiency (HGHD) after analysing the sellar MRI signals of them.Materials and Methods: Results of 65 patients MRI signals of sella, including 50 patients with PGHD, 15 patients with HGHD and the statistical methods including discriminated analysis, test, χ 2 test had been used in this study. All patients are divided into two groups, the statistical (47 cases ) and the test group (18 cases).Results: The height of pituitary (X1), the posterior lobe of pituitary (X2), the pituitary stalk (X3) and sellar fossa (X4) are the important indexes to diagnose PHGD and HGHD. The rate of correct diagnosis according to the discriminants in about 88.9‰.Conclusion: The discriminants are of important value in the differential diagnosis of PGHD and HGHD.
出处
《临床放射学杂志》
CSCD
北大核心
1997年第3期133-135,共3页
Journal of Clinical Radiology
