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肺炎及上呼吸道感染患者血清氨基末端脑钠素前体与心肌酶谱测定的临床意义 被引量:1

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摘要 目的:测定肺炎、上呼吸道感染患者血清中氨基末端脑钠素前体(NT-proBNP)、心肌酶谱水平,探讨其临床意义。方法:利用OLYMPUS AU600生化分析仪测定患者和对照组血清中心肌酶谱水平,在ANALYTICS E170光电免疫发光仪上对血清NT-proBNP的含量进行检测。结果:(1)肺炎组血清中NT-proBNP含量较对照组明显升高(P<0.01),异常率为85.63%;心肌酶谱水平较对照组明显升高(P<0.01),异常率按照LDH-L、CK、AST、HBDH、CK-MB依次降低,分别为48.28%、37.93%、30.05%、25.12%、15.76%。(2)上呼吸道感染组血清中NT-proBNP含量较对照组有所升高(P<0.05),心肌酶谱中仅CK水平高于对照组(P<0.05),AST、LDH-L、CK-MB水平无明显改变,异常率按照LDH-L、CK、HBDH、AST、CK-MB依次降低,分别为21.32%、15.85%、11.37%、10.23%、5.96%。结论:肺炎患者存在一定程度的心肌损伤,心肌酶谱升高是普遍的,可能是由病原体感染产生的毒素及疾病造成的组织缺氧引起,并不一定都是心肌炎或心肌损害所致,不排除其他器官组织的损害。上呼吸道感染患者心肌损伤较肺炎患者轻,可能同时发生骨骼肌的损伤。
出处 《实用医学杂志》 CAS 2007年第7期1066-1067,共2页 The Journal of Practical Medicine
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