摘要
葡萄糖几乎是脑组织能量的惟一来源,脑的生理活动或病理过程都伴随着葡萄糖代谢水平的变化,不同脑区葡萄糖代谢水平可客观地反映脑局部功能状态。研究葡萄糖代谢的变化规律对于阐明能量代谢紊乱在中枢神经系统疾病中的地位、作用及其凋控机制具有重要意义。活体、组织和细胞中葡萄糖代谢的研究方法各有不同,在实验研究中多采用放射性核素标记示踪剂,而功能影像学技术则为脑功能研究注入了新的活力。
Glucose is almost the only energy source of brain tissues. Both physiological activities and pathological processes of brain accompany the changes of glucose metaboilic levels. The glucose metabolic levels in different brain regions can objectively reflect the brain regional functional states, The study of the changing law of glucose metabolism has important significance for clarifying the status, roles and its regulating mechanisms of energy metabolic disorder in the central nervous system diseases, The research methods of glucose metabolism in living body, tissues and cells are different, in which radioisotope labeling is usually used, but the functional imaging techniques have brought new energy to brain functional research.
出处
《国际脑血管病杂志》
2006年第10期785-788,共4页
International Journal of Cerebrovascular Diseases
关键词
脑
葡萄糖代谢
糖酵解途径
磷酸戊糖途径
brain
glucose metabolism
glycolytic pathway
pentose phosphate pathway
