摘要
目的：观察罗红霉素治疗小儿呼吸道感染的疗效。方法：选择小儿呼吸道感染655例,分为治疗组(A)345例,对照组(B)310例,其中深圳328例,武汉327例。治疗组血样正常226例,深圳114,武汉112例,WBC增加119例,深圳59例,武汉60例,对照组,血样正常196例,深圳98例,武汉98例。白血球增加114例,深圳57例,武汉57例,治疗组用罗红霉素5 mg·kg^(-1)·d^(-1),po bid,5～7 d,对照组用青霉素,哌拉西林,或头孢菌素5～7 d。所有患者都进行胸部超短波理疗,口服急支糖浆治疗。结果：治疗组有效率：深圳91．8%,武汉96．5%。对照组有效率：深圳74．9%,武汉74．7%；治疗组与对照组间有效率差异显著P＜0．05；结论：罗红霉素对小儿呼吸道感染疗效好、安全方便。
Objective： To observe the curative effect of roxithromycin on respiratory tract infections （RTI） in children. Method： Of 655 children with RTI, who were divided into 1treatment group （ A ） （ 345 cases） and control group （B） （310 cases）, 328 were treated in Shenzhen City Children＇s Hospital and 327 in Wuhan General Hospital. In the treatment group, the hemogram was normal in 226 children, of whom, 114 were in Shenzhen and 112, in Wuhan, and WBC increased in 119 Children, of whom, 59 were in Shenzhen and 60, in Wuhan. In the control group, the hemogram was normal in 196 children, of whom, 98 were in Shenzhen and 98, in Wuhan, and WBC increased in 114 children, of whom, 57 was in Shenzhen and 57, in Wuhan. All the children in the treatment group were treated with roxithromycin （5 mg·kg^-1·d^-1 Bid, P. O） for 5-7 days. All the children in the control group were treated with penicillin, piperacillin or cephalosporious for 5-7 days. All the children in both groups received physicotherapeutics and took Jizhi Couth Syrup at the same time. Result： The effective rates in the treatment group were 91.9% in Shenzhen and 96.5% in Wuhan. The effective rates in the control group were 74.9% in Shenzhen and 79.9% in Wuhan. There was significant difference in the effective rates between the treatment group and control group （ P 〈 0.05）, Conclusion ： The treatment of the children with RTI is good in the curative effect, convenient and also safe.
出处
《药物流行病学杂志》
CAS
2006年第5期261-263,共3页
Chinese Journal of Pharmacoepidemiology
关键词
罗红霉素/药物治疗
呼吸道感染/小儿
Roxithromycin
Children
Respiratory tract infection
Curative effect
