摘要
目的探讨间苯三酚静脉注射配合徒手扩张宫颈缩短产程的效果。方法将240例初产妇随机分为3组各80例。分娩过程中待宫口开大3cm时,观察组采用间苯三酚80mg静脉注射配合徒手扩张宫颈口;对照1组用地西泮10mg缓慢静脉注射,不扩张宫颈口;对照2组用间苯三酚80mg静脉注射,不扩张宫颈口。比较三组产妇分娩时总产程时间、产后出血量、新生儿窒息及剖宫产率。结果观察组产妇总产程时间、新生儿窒息与对照1组及对照2组比较,差异有显著性意义(P<0.05,P<0.01);剖宫产率较对照1、2组显著下降(P<0.05,P<0.01);3组产后出血量比较,差异无显著性意义(均P>0.05),对照1组药物不良反应发生率显著高于观察组及对照2组(均P<0.01)。结论静脉注射间苯三酚配合徒手扩张宫颈能加速产妇宫颈口扩张,缩短产程,而且对母婴安全无显著不良影响。
Objective To examine the effect of intravenous injection of phloroglucinol plus hand cervical dilation. Methods Two hundred and forty primiparas were divided into 3 groups, with 80 women in each group. When the orifice of uterus was 3 cm wide, the intravenous injection of phloroglucinol （80 rag） plus hand cervical dilation was used for the experimental group; diazepam （80 mg） was given, without cervical dilation, in control group 1; intravenous injection of phloroglucinol （80 mg） was given, without cervical dilation, in control group 2. The total stage of labor, postpartum bleeding, apnoea of neonates, the rate of Cesarean section were compared among the three groups. Results There were significant differences in total stage of labor and apnoea of neonates between the experimental groups and the control groups 1 and 2 （P〈0.05, P〈0.01）, The rate of cesarean section was lower than those of the control groups 1 and 2 （P〈0.05, P〈0.01）. No significant differences were found among the 3 groups in the amount of postpartum hemorrhage （P〉0.05 for all）. In the control group 1, the rate of drug adverse reaction was significantly higher than those of the experimental group and control group 2 （P〈0.01 for all）. Conclusion Intravenous injection of phloroglucinol plus hand cervial dilation can accelerate the dilation cervical orifice, short the time of labor and has no adverse effect on mother and baby.
基金
2005年度佛山市卫生局医学科研立项课题(2005461)
关键词
初产妇
间苯三酚
徒手扩张宫颈
分娩
primipara
phloroglucinol
hand cervical dilation
labor
