摘要
目的:探讨中药益气固肾液对慢性肾衰维持性血透(MHD)患者前炎症细胞因子的影响的临床研究。方法:(MHD)患者60名,随机分为治疗组和对照组各30例,治疗组在常规治疗中加入中药益气固肾液治疗,对照组为常规血液透析液,疗程为3个月,观察中药干预后患者临床症状以及血清TNF-a、IL-6等变化。结果:治疗组与对照组治疗后比较,血浆TNF-a水平明显下降(P<0.05),血清IL-6也有下降,但无统计学差异,提示中药益气固肾液能改善血透患者的微炎症状态,从而改善营养不良—炎症—动脉粥样硬化综合征(MIA)。
Objective： To investigate the affection of Yiqigushen liquid medicine （strengthening- qi - and reinforcing- kidney liquor） on chronic inflammatory state of CRF patients by detecting and comparing the biochemical indicators and TNF - a, IL- 6 levels in patients of Maintain Hemodialysis （MHD） patients. Method： 60 cases of MHD patients were randomly allocated into two groups： treatment group and control group, 30 cases in each. The duration of the therapy was three months. Conventional dialysis liquid of sodium bicarbonate was used in the control group, while Yiqigushen liquid medicine was added in the treatment group. Results： TNF-a level of the treatment group were lower than that of the control group with statistical significance （p 〈 0. 05） ; IL - 6 level of the treatment group also showed to be lower in the treatment group but without statistical significance （p 〉 0. 05）. From which we conclude that Yiqigushen liquid medicine can improve the state of chronic inflammation to some extent, improve the state of malnutrition, decrease the incidence of the vascular disease, so will improve the MIA.
出处
《云南中医学院学报》
2006年第3期18-21,共4页
Journal of Yunnan University of Traditional Chinese Medicine
基金
广东省重点科技攻关项目。(NO:2002C10804)
