摘要
目的：了解椎体和股骨近端松质骨在骨代谢中的关系以及椎体定量ＣＴ（ＱＣＴ）测量在检测近端股骨骨质疏松的临床意义。材料与方法：对２０～５９岁正常人（男、女各１００例）的第３腰椎和近端股骨的松质骨做了ＱＣＴ测量，对测量结果进行了统计学相关性分析。在１个月内对１０例受试者的腰椎、近端股骨进行了４次测量，测量在同一层面采用同一扫描条件，对两部位的测量精确性进行了计算。结果：椎体与近端股骨松质骨矿物质含量（简称骨矿含量）在自身个体中存在显著的相关性，男、女总体相关系数ｒ分别为０．８６和０．８２（Ｐ＜０．００１），且均随年龄增长两部位骨矿含量逐年减少。ＱＣＴ对腰椎和近端股骨测量的精确性分别为１．８％和３％。结论：椎体和股骨近端松质骨结构和代谢一致，由于椎体ＱＣＴ测量方法简便，在检测骨矿含量变化、诊断骨质疏松症方面可替代测量较为烦琐的股骨ＱＣＴ测量。
Purpose:Todefinethecorrelationofthetrabecularboneofthelumbarvertebraasrelatedtoproximalfemurinbonemetabolism,andtheclinicalsignificanceofthequantitativeCT(QCT)densitometryinosteoporosisoftheproximalfemur.Materialsandmethods:200casesofnormalindividuals(100men,100women;age,20 59years)werestudiedwithQCTdensitometryatsiteofthethirdlumbarvertebraandproximalfemur.Theresultswereanalysedstatisticaly.An-other10casesweremeasuredatsameareaofthelumbarvertebraandproximalfemur4timesinonemonthtodeterminetheprecisionofdensitometry.Results:Significantcorelationwasfoundbetweenthelumbarvertebraandproximalfemurineverycasewithoveralcorrelationfactorsr=0.86and0.82inthemaleandfemalerespectively(P<0.001).Thebonemineralcontent(BMC)decreasedwithage.Theprecisionofdensitometrywas1.6%and3.0%inlumbarvertebraandproximalfemurrespectively.Conclusion:Thetrabecularboneofthevertebraorproximalfemurhadsignificantcor-relationwithbonemetabolism.ItwasconcludedthatvertebraQCTmayreplacefemurQCTinmea-suringBMCanddiagnosingosteoporosisbecauseofitssimplicityandequivalentaccuracy.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
1996年第5期317-320,共4页
Chinese Journal of Radiology
关键词
骨密度
CT
骨质疏松
腰椎
股骨
BonemineralcontentTomography,X-raycomputedDensitometryOs-teoporosis
